[1] Zhang Zhiguo Xue Zhiwen Zhang Zhuohong Zhang Lili Wu Yanmei,.Comparative Observation on Clinical Effect and Safety of Aerosol Inhalation and Intramuscular Injection of Chuankezhi in Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease [J]. Modern Traditional Chinese Medicine, 2017, (06): 13-15. [doi: 10.13424/j.cnki.mtcm.2017.06.006]
Comparative Observation on Clinical Effect and Safety of Aerosol Inhalation and Intramuscular Injection of Chuankezhi in Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Modern Traditional Chinese Medicine[ISSN: 1006-6977/ CN: 61-1281/TN]
Volumes & Issues:
2017 06
pagination:
13-15
Column:
Publication date:
2017-11-01
- Article number:
- 1672-0571(2017)06-0013-03
- ZTFLH:
- Ｒ563
- Code:
- A
- Abstract:
- Objective to observe comparatively the clinical effect and safety of aerosol inhalation and intramuscular injection of Chuankezhi in Treating AECOPD.Method 98 AECOPD patients treated by Xi an XD Group Hospital from March 2015 to May 2017 were selected and randomly divided into treatment group and control group with 49 cases in each by the envelop method.All the patients received conventional therapy such as oxygen inhalation,cough relief,antiasth-ma,anti-infection and acid-base balance correction.Based on that,cases in control group were given intramuscular injection of Chuankezhi while the treatment group were given aerosol inhalation of Chuankezhi.The course for each group were 7 days.Clinical efficacy rate,incidence of adverse reactions,improvement of lung function and quality of life before and after treatment of both groups were observed.Result Clinical efficacy rates of treatment group and control group were 69.39%and 75.51%,respectively,incidences of adverse reactions of the two groups were 2.04%and 12.24%,re-spectively,the differences had no statistical significance(P>0.05).Before the treatment,the difference of FEV1,FEV1/FVC,dyspnea scores and 6WMT of the two groups had no statistical significance(P>0.05).After 7 days of treat-ment,all the indicators of the two groups had significantly improved,the difference within the same group was statistically significant(P<0.05),but the difference between the two groups had no statistical significance(P>0.05).Conclusion The clinical effect,safety,the improvement of lung function and life quality of aerosol inhalation and intramuscular injection of Chuankezhi in treating AECOPD are equivalent,and is worthy of clinical application.
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收稿日期:2017-03-22编辑:巩振东
Last Update:
2017-11-15