[1] Jiang Xiaoyan Tang Haihong Wei Chunshan Tong Guangdong Zhou Daqiao Huang Bin,.Treatment of 31 Cases of Primary Biliary Cholangitis with Ruangan Decoction Combined with Ursodeoxycholic Acid [J]. Modern Traditional Chinese Medicine, 2018, (06): 33-35. [doi: 10.13424/j.cnki.mtcm.2018.06.013]
Treatment of 31 Cases of Primary Biliary Cholangitis
with Ruangan Decoction Combined with Ursodeoxycholic Acid
- Article number:
- 1672－0571(2018)06－0033－04
- Keywords:
- knee osteoarthritis; method of invigorating kidney and boosting Qi; Chinese medicine treatment; quali- ty of life
- ZTFLH:
- R575. 7
- Code:
- B
- Abstract:
- To observe the clinical effect of Ruangan decoction combined with ursodeoxy- cholic acid in treating primary biliary cholangitis． Method: Sixty － four patients with primary biliary cholangitis (PBC) from 2016． 5 to 2017． 5 in Shenzhen TCM Hospital were randomly divided into con- trol group and treatment group according to the number table method． They were treated with drugs for 6 months and followed up during the treatment period． The control group was treated with Ursodeoxycholic Acid Capules，and the treatment group was treated with Rugan decoction combined with ursodeoxycholic acid． The enzyme，immune index，Firbscan value，syndrome score and effective rate were observed and compared． Result: The TB level in the treatment group before treatment was higher than that in the con- trol group (P ＜ 0． 05)，and there was no difference in the remaining baseline indicators． After treat- ment，ALT，AST，GGT，TB，ALP，IgM，Ig g，complement C3，Firbscan values and syndrome scores showed significant differences in the treatment group，the differences were statistically significant(P ＜ 0． 05)． ALT，AST，GGT，TB，ALP，Ig g and Firbscan values showed significant differences in thecontrol group，the differences were statistically significant(P ＜0． 05)． The total effective rate of GGT、 TB、ALP、IgM、Ig g、Firbsca values and syndrome scores in the treatment group were better than those in the control group (P ＜ 0． 05)． No adverse events occurred during the treatment． Conclusion: Ruangan decoction combined with ursodeoxycholic acid is effective and safe in the treatment of primary biliary cholangitis．
References:
[1]中华医学会．临床诊疗指南消化系统疾病分册［Ｍ]．北 京：人民卫生出版社，２００５：８７－８８．
[2]ＲｕｎｙｏｎＢＡ．ＭａｎａｇｅｍｅｎｔｏｆＡｄｕｌｔＰａｔｉｅｎｔｓＷｉｔｈＡｓｃｉｔｅｓ ＣａｕｓｅｄｂｙＣｉｒｒｈｏｓｉｓ［Ｊ]．Ｈｅｐａｔｏｌｏｇｙ，２００９，４９（６）：２０８７ －２１０７．
[3]冯鑫，闫杰．２０１０年欧洲肝脏研究协会《肝硬化腹水、 自发性细菌性腹膜炎、肝肾综合征临床实践指南》简 介［Ｊ]．胃肠病学和肝病学杂志，２０１１，２０（３）：２９１ －２９４．
[4]周仲瑛，金实，李明富，等．中医内科学［Ｍ]．新世纪第 二版．北京：中国中医药出版社，２００９：２８３－２８５．
[5]金银鹏，傅青春．肝硬化腹水诊治进展—ＡＡＳＬＤ２０１２版 肝硬化腹水诊疗指南介绍［Ｊ]．肝脏，２０１３，１８（９）：６３８ －６４０．
[6]刘成海，姚树坤．肝硬化腹水的中西医结合诊疗共识意 见［Ｊ]．中 国 中 西 医 结 合 杂 志，２０１１，３１（９）：１１７１ －１１７４．
[7]高风琴，杨跃青，何瑾瑜，等．鼓胀病的中医证候文献研 究［Ｊ]．陕西中医，２０１２，３３（３）：３０７－３１０．
[8]田莉婷，杨海侠，李煜国，等．温补脾肾化气利水法对肝 硬化腹水醛固酮的影响［Ｊ]．陕西中医，２０１４，３５（２）： １７１－１７３．
[9]李妮矫，王君，姚树坤．湿热证与肝脏炎症指标的相关 性研究［Ｊ]．中国中医基础医学杂志，２０１１，１７（３）：２９４ －２９５．
[1０]张春光，朱媛雯．益气健脾化浊汤治疗肝硬化低蛋白 血症 ３０例临 床 观 察 ［Ｊ]．浙 江 中 医 杂 志，２０１５，５０ （１）：２５．
[1１]史文丽，张彼，孙永强．肝炎肝硬化低蛋白血症的中医 证候特点及疗效分析 ［Ｊ]．北京中医药大学学报， ２００９，１６（６）：７－１０．
[1２]赵志超，卢秉久．肝硬化腹水中医证型与检测指标相 关性分析［Ｊ]．世界中西医结合杂志，２０１２，７（８）：６８０ －６８２．
[1３]周艾强，周树录，王健，等．乙肝肝硬化合并凝血功能 紊乱的中医证候研究［Ｊ]．中医临床研究，２０１６，８ （２８）：１－４．
Memo
收稿日期:2017 －11 －01 编辑:杨芳艳