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[1] Yan Mingxia,.Effect of Yangxin Tongbi Decoction Combined with Routine Thrombolytic Therapy on Patients with Acute Myocardial Infarction [J]. Modern Traditional Chinese Medicine, 2019, (03): 38-41. [doi: 10.13424/j.cnki.mtcm.2019.03.013]

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Effect of Yangxin Tongbi Decoction Combined with Routine Thrombolytic Therapy on Patients with Acute Myocardial Infarction

Modern Traditional Chinese Medicine[ISSN: 1006-6977/ CN: 61-1281/TN] Volumes & Issues: 2019 03 pagination: 38-41 Column: Publication date: 2019-05-30

Article number:: 1672-0571(2019)03-0038-04

Author(s):: Yan Mingxia; Shanyang TCM Hospital, Shanyang Shaanxi, 726400

Keywords:: acute myocardial infarction; myocardial ischemia; reperfusion injury; Yangxin Tongbi Decoction; thrombolytic therapy

ZTFLH:: R255.2

DOI:: 10.13424/j.cnki.mtcm.2019.03.013

Code:: A

Abstract:: To explore the effect of Yangxin Tongbi Decoction combined with routine thrombolytic therapy on myocardial ischemia - reperfusion injury index in patients with acute myocardial infarction. Methods: According to the random number table method, all patients were randomly divided into treatment group and control group. All patients were given routine thrombolytic therapy, while patients in treatment group were treated with Yangxi Tongbi Decoction additionally. The levels of creatine kinase isoenzymes and creatine kinase, hypersensitive C - reactive protein and hypersensitive troponin were recorded before and after treatment. Left ventricular ejection fraction, myocardial infarction area and adverse reactions were compared between the two groups before and after treatment. Results: After treatment, the levels of TNT - HS, CK - MB, CK, hs - CRP in the two groups were significantly better than those before treatment; the levels of TNT - HS, CK - MB, CK, hs - CRP in the treatment group were significantly better than those in the control group. The left ventricular ejection fraction and myocardial infarction area of the two groups after 1 day and 7 days of treatment weresignificantly better than those before treatment; the left ventricular ejection fraction of the treatment group was significantly higher than that of the control group after 1 day of treatment and 7 days of treatment; the myocardial infarction area of the treatment group was significantly lower than that of the control group after 1 day of treatment and 7 days of treatment. The incidence of reperfusion arrhythmia and adverse cardiovascular events in the treatment group were 6. 67% and 6. 67%, respectively, lower than those in the control group ( 26. 27% and 33. 33%) . Conclusion: Conventional thrombolysis combined with Yangxin Tongbi Decoction can effectively improve the reperfusion injury in patients with acute myocardial infarction, and can effectively avoid adverse cardiovascular events and promote the recovery of left ventricular ejection function. It is worth popularizing in clinical practice.

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Last Update: 2019-05-15