[1] WU Shuang CHANG Pengcheng YUE Xiaofeng ZHOU Zhihuan,.Construction of Prescription Compatibility Information Mining System and Analysis of Compatibility Law of Palpitation Ancient Prescription [J]. Modern Traditional Chinese Medicine, 2022, 1(03): 37-42. [doi: 10.13424/j.cnki.mtcm.2022.03.007]
Construction of Prescription Compatibility Information Mining System and Analysis of Compatibility Law of Palpitation Ancient Prescription
- Article number:
- 1672-0571(2022)03-0037-06
- Keywords:
- Key words：Traditional Chinese medicine; Prescription; Excavation system; Palpitation; Compatibility law
- ZTFLH:
- R289.1
- Code:
- A
- Abstract:
- Abstract：Objective To construct a comprehensive mining system of prescription compatibility information and analyze the compatibility law of ancient prescriptions for the treatment of palpitation.Methods The prescriptions for the treatment of palpitation in the Dictionary of Traditional Chinese Medicine Prescriptions and Zhong Hua Yi Dian were collected and sorted out，and the obtained information was standardized.A comprehensive mining system for prescription compatibility information was established.The compatibility law，dosage form and syndrome type of prescriptions were analyzed by data mining and bibliometric methods.Results ① Song Dynasty prescriptions accounted for the highest proportion of palpitation ancient prescriptions，followed by Ming and Qing prescriptions.② The dosage form of palpitation ancient prescription is pill，followed by decoction，powder and wine.③ Among the 233 ancient prescriptions collected，Ginseng has the highest frequency，followed by Licorice，Polygala tenuifolia，Poria，Poria cocos，Ophiopogon japonicus，Cinnabar，Angelica sinensis，Wild jujube kernel，Acorus calamus，Atractylodes macrocephala，Longchi and Fangfeng，among which tonic drugs and tranquilizing drugs are the most；④ According to the analysis of common drug pairs in palpitation ancient prescription，Ginseng-Polygala tenuifolia and Ginseng-Fushen are the most frequent drug pairs；⑤ Association rule analysis showed that，(Polygala tenuifolia - Fushen) - ＞Ginseng，(Ophiopogon japonicus - Licorice) -＞Ginseng，(Licorice - Fushen) -＞Ginseng were compatibility with confidence greater than 0.80；⑥ Palpitation syndrome type is mainly mixed with deficiency and excess syndrome.Conclusion The compatibility analysis of ancient prescriptions for the treatment of palpitation can provide a certain reference basis for the clinical treatment of palpitation based on syndrome differentiation.
References:
［1]王永炎.临床中医内科学［J].北京出版社,1994.
［2]姜瑞雪,朱文锋,马作峰.心悸的中医病因病机源流探析［J].光明中医,2007,22(9):15-18.
［3]国家药典委员会.中华人民共和国药典［S].三部.北京:化学工业出版社,2005.
［4]国家中医药管理局《中华本草》编委会.中华本草-9［M].上海:上海科学技术出版社,1999.
［5]张臻,高天慧,傅超美,等.中药丸剂剂型理论与应用现状关键问题分析［J].中国中药杂志,2017,42(12):2408-2412.
［6]耿晓娟,阮士怡,张军平.心悸病因病机及方药演变初探［J].中医杂志,2018,59(20):1717-1721.
［7]田静,任雨贺,刘淑莹,等.人参皂苷Re对心血管系统的药理作用研究进展［J].安徽农业科学,2019,47(6):23-25.
［8]毕春和,康有周.炙甘草汤加减治疗心律失常室性早搏50例［J].云南中医中药杂志,2011,32(11):53-54.
［9]彭程万.炙甘草汤治疗频发房性早搏临床研究［J].河南中医,2014,34(6):1011-1012.
［10]富嫱.炙甘草汤辨治缓慢性心律失常［J].实用中医内科杂志,2016,30(8):47-48.
［11]毕颖斐,毛静远.炙甘草汤在缓慢性心律失常治疗中的应用及探讨［J].天津中医药,2016,33(8):465-466.
［12]杨亚琴,谢子明.炙甘草汤加减治疗恶性肿瘤患者放化疗后虚劳性心悸56例［J].光明中医,2012,27(2):257-258.
［13]吕妮娜,蒙智扬.炙甘草汤治疗心律失常对患者心功能的影响观察［J].内蒙古中医药,2021,40(3):13-15.
［14]王兵,王亚新,赵红燕,等.甘草的主要成分及其药理作用的研究进展［J].吉林医药学院学报,2013,34(3):215-218.
［15]刘大伟,康利平,马百平.远志化学及药理作用研究进展［J].国际药学研究杂志,2012,39(1):32-36,44.
［16]李时珍.本草纲目［M].太原:山西科学技术出版社,2014:976.
［17]陶弘景.名医别录彩色药图［M].陈芳,杨卫平主编.贵阳:贵州科技出版社,2017:19.
［18]罗伯承,何宜荣.方剂组方配伍理论的研究进展［J].湖南中医杂志,2011,27(2):128-129.
［19]李镇,容悦莹,王淑美,等.中药组方配伍的研究进展［J].中国实验方剂学杂志,2015,21(7):223-226.
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基金项目：国家973项目（2012CB518401）