[1] LIU YueZHANG ChaojuHE ChuanLI XiaolinLIU DaodongCHEN HongweiPENG ChanghuaWANG Huadong,.Clinical Study on Combination of Shujin Zhixuan Decoction andFlunarizine Hydrochloride in the Treatment of CervicalVertigo with Phlegm Dampness Obstruction Syndrome [J]. Modern Traditional Chinese Medicine, 2024, (03): 52-57. [doi: 10.13424/j.cnki.mtcm.2024.03.010]
Clinical Study on Combination of Shujin Zhixuan Decoction andFlunarizine Hydrochloride in the Treatment of CervicalVertigo with Phlegm Dampness Obstruction Syndrome
- Article number:
- 1672-0571(2024)03-0052-07
- Keywords:
- Key words:Cervical vertigo; Shujin Zhixuan decoction; Flunarizine Hydrochloride; Phlegm dampness obstructing collaterals syndrome
- ZTFLH:
- R255.3
- Code:
- A
- Abstract:
- Abstract：Objective To explore the clinical effect of Shujin Zhixuan decoction combined with Flunarizine Hydrochloride in the treatment of cervical vertigo with phlegm dampness obstruction syndrome.Methods Sixty patients with cervical vertigo were randomly divided into a treatment group and a control group，with 30 cases in each group；The treatment group received oral administration of Shujin Zhixuan decoction combined with Flunarizine Hydrochloride capsules for treatment，while the control group received oral administration of Flunarizine Hydrochloride capsules for treatment for 2 weeks.The treatment effects and changes in blood rheology and hemodynamics before and after treatment were compared between the two groups of patients.Results The total effective rate of the treatment group was 86.67%，significantly better than the control groups 63.33%，with a statistically significant difference (P<0.05)；After treatment，the hemorheological indicators (whole blood high shear viscosity，plasma viscosity，hematocrit，whole blood low shear viscosity) and hemodynamic indicators (vertebral basilar artery average blood flow velocity) of both groups improved compared to before treatment，and the treatment group had better indicators than the control group，with statistical significance (P<005)；During the treatment，both groups of patients did not experience significant adverse reactions such as palpitations，chest tightness，nausea and vomiting，abdominal pain，diarrhea，or worsening symptoms of dizziness.Conclusion The combination of Shujin Zhixuan decoction and Flunarizine Hydrochloride capsules has more advantages in treating cervical vertigo.It can effectively reduce blood viscosity and improve blood circulation，promote cerebral blood supply，and thereby improve symptoms such as dizziness，upper limb numbness，and neck stiffness and pain.
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Memo
基金项目：2022年全国名老中医药专家传承工作室建设项目(国中医药人教函〔2022〕75号)