[1] Sun Jianfei Zhang Xilu Li Zahnrong Wu Xuchu Lei Ting Zhou Jun,.Influence of Tongfu Huoxue Prescription over Postoperative Intestinal Adhesion [J]. Modern Traditional Chinese Medicine, 2017, (04): 99-103. [doi: 10.13424/j.cnki.mtcm.2017.04.036]
Influence of Tongfu Huoxue Prescription over Postoperative Intestinal Adhesion
- Article number:
- 1672－0571(2017)04－0100－05
- ZTFLH:
- Ｒ285.5
- Code:
- A
- Abstract:
- Objective: To prove that Tongfu Huoxue Prescription can effectively prevent postoperative intestinal ad- hesion and primarily explore its mechanisms by preparing the SD rats model with postoperative intestinal adhesion． Meth- od: Totally 40 rats were randomly divided into 4 groups: normal，model，Dahuangchong Pill and Tongfu Huoxue Prescrip- tion group with equal numbers． On the 7th day after operation，the adhensive degrees in all groups were defined，the ser- um IL－6 and TNF－α concentrations were checked by ELISA and the conditions of intestinal distension as well as blood circulation were observed under X－ray and ultrasound． Ｒesults: The adhesive degrees in Dahuangchong Pill and Tongfu Huoxue Prescription group were lower than in the model group ( P＜0．05) and the IL－6 and TNF－α levels in these two groups were lower than the model group on the 7th day after operation ( P＜ 0．01) ． X－ray and ultrasound results: The blood circulation of Tongfu Huoxue Prescription group was better，the bowel movements were more frequent and air accu- mulating in the cavity significantly reduced，compared with the model group． Conclusion: Tongfu Huoxue Prescription is able to decrease the IL－6 and TNF－α levels，promote bowel movement and lighten intestinal distention to prevent the oc- currence of rats’postoperative intestinal adhesion．
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Memo
收稿日期:2016－06－08编辑:文颖娟＊＊
基金项目:陕西省教育厅资助项目(2010JK514)
通讯作者:李展绒(1975－)，女，主管护师，研究方向:外科护理。E－mail:1342497530@qq．com