[1] Liu Ling, Liu Deliang, Li Huilin, et al. On Treatment of 30 Cases of Type 2 Diabetes with Qi-Yin Deficiency Syndrome by Huoxue Jiangtang Potion [J]. Modern Traditional Chinese Medicine, 2017, (05): 16-20. [doi: 10.13424/j.cnki.mtcm.2017.05.007]
On Treatment of 30 Cases of Type 2 Diabetes with Qi-Yin Deficiency Syndrome by Huoxue Jiangtang Potion
- Article number:
- 1672一0571(2017)05一0016一O5
- ZTFLH:
- R255.4
- Code:
- A
- Abstract:
- Objective:To investigate the therapeutical effect of Huoxue Jiangtang potion on patients of type 2 diabetes with qi-yin deficiency syndrome and its effect on DPP-4activity.Methods:60patients with type 2di- abetes from both the outpatient and inpatient departments were randomized into treatment group and control group with 30case in each.Both groups were orally given sitagliptin phosphate and the cases of the treatment group were additionally given Huoxue Jiangtang potion.The patients age,sex,course of the disease,syndrome integral before and after the treatment,fasting and 2hpostprandial blood glucose,fasting and 2hpostprandial plasma insulin,fasting and postprandial DPP-4enzyme activity were recorded.Results:After the treatment, the syndrome integral,fasting and 2hpostprandial blood glucose as well as fasting and postprandial DPP-4enzyme activity decreased significantly,while the fasting and 2hpostprandial plasma insulin increased greatly,the differences had statistical significance(P<0.05,P<0.01).The syndrome integral,2hpostprandial blood glu- cose,2hpostprandial plasma insulin and 2hpostprandial DPP-4enzyme activity of the treatment group decreased more significantly than those of the control group after the treatment,the differences were statistically significant(P<0.05,P<0.01).The differences before and after the treatment in the syndrome integral,2h postprandial blood glucose,2hpostprandial plasma insulin and 2hpostprandial DPP-4activity of the treatment group increased more significantly than those of the control group and had statistical significance(P<0.05,P<0. 01).Conclusion:Huoxue Jiangtang potion can improve the clinical symptoms of patients of type 2diabetes with qi-yin deficiency,reduce fasting and postprandial blood glucose,increase fasting and postprandial insulin secretion.It is more effective in improving fasting blood glucose and insulin than in postprandial conditions and its effect may be related to reducing postprandial DPP-4enzyme activity.
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Memo
收稿日期:2016-10-05编辑:巩振东
通讯作者:李惠林(1963-)，男，博士研究生，教授，主任医师，广东省名中医，从事中医药防治内分泌及代谢性疾病的诊治与研究。E-mail：sztcmLhl@163.com