[1] Yao Minna Dou Fang Li Ruili Zhang Wei Bu Wei Zhang Wangping Wen Aidong Yang Zhifu,.Study on the Improvement of Quality Standard for Desheng Capsule [J]. Modern Traditional Chinese Medicine, 2018, (06): 127-131. [doi: 10.13424/j.cnki.mtcm.2018.06.043]
Study on the Improvement of Quality Standard for Desheng Capsule
- Article number:
- 1672－0571(2018)06－0127－06
- Keywords:
- Desheng Capsule; quality standard; HPLC; TLC; microbial limit test
- ZTFLH:
- R285. 5
- Code:
- A
- Abstract:
- To establish quality standard for Desheng Capsule． Method: The microscopic fea- tures of the carapax trionycis were identified by microscope． The ginseng and turmeric in Desheng Cap- sule were qualitatively identified by TLC method，which was verified by the 2015 edition of Chinese Pharmacopoeia． HPLC was used to determine the content of emodin in Rhubarb． Result: The microscopic features were obvious; TLC identified ginseng and turmeric characteristic spots were clear and the reso- lution was good; the microbial limit test of the capsules could be carried out by the plate method and the direct inoculation method; the content of emodin was linear in the range of 0． 02002 ～0． 2002 μg ( r = 0． 999 8)，the average recovery was 98． 04%，and the RSD was 1． 63% (n = 6)． Conclusion: The method is simple，highly specific and reproducible，and can be used as a quality control method for Desheng Capsule．
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Memo
收稿日期:2018 －03 －20 编辑:文颖娟＊
＊ ＊
基金项目:军队医疗机构制剂标准提高科研专项课题( 14ZJZ16 －1)
通讯作者:杨志福 (1973 － )，男，博士，教授，硕士生导师，研究方向:中药新药研发。E － mail:yangtian_1973@ 163．
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