[1] LIU Haitao LI Qisu HU Jingyu NIU Dengfeng LIU Zhenghui,.Clinical Study on Treatment of Liver and Stomach Stagnation Type Bile Reflux Gastritis by Modified Yueju Wendan Decoction and Acupoint Application [J]. Modern Traditional Chinese Medicine, 2023, (04): 60-64. [doi: 10.13424/j.cnki.mtcm.2023.04.012]
Clinical Study on Treatment of Liver and Stomach Stagnation Type Bile Reflux Gastritis by Modified Yueju Wendan Decoction and Acupoint Application
- Article number:
- 1672-0571(2023)04-0060-05
- Keywords:
- Key words:Bile reflux gastritis; Liver and stomach stagnation heat; Yueju Wendan decoction; Acupoint application
- ZTFLH:
- R244.9
- Code:
- A
- Abstract:
- Abstract：Objective To observe the clinical efficacy of modified Yueju Wendan decoction combined with acupoint application in the treatment of bile reflux gastritis of liver stomach stagnation heat type.Methods According to the method of random number table,93 patients with bile reflux gastritis (liver stomach heat stagnation type) were randomly divided into the treatment group (47 cases) and the control group (46 cases).The treatment group was treated with Yueju Wendan decoction plus acupoint application,and the control group was treated with trimebutine maleate,rabeprazole enteric coated capsules,and aluminum magnesium dimethicone oil chewable tablets;The course of treatment was 8 weeks.The clinical efficacy,symptom score,endoscopic changes of gastric mucosa and adverse reactions were observed before and after treatment in both groups,and the efficacy was comprehensively evaluated.Results The total effective rate of the treatment group (93.61%) was significantly higher than that of the control group (82.60%),and the difference between the two groups was statistically significant (P<0.05).After treatment,the symptoms of both groups improved significantly,and the clinical symptom scores showed a statistically significant difference compared to before treatment (P<0.01).After treatment,the clinical symptom scores of the treatment group showed a statistically significant difference compared to the control group (P<0.05).The treatment group had a better effect than the control group in improving reflux and glandular atrophy (P<0.05),and there was no statistically significant difference in improving mucosal congestion,edema,erosion,and intestinal metaplasia (P>0.05).Conclusion The combination of modified Yueju Wendan decoction and acupoint application has a significant therapeutic effect on bile reflux gastritis,which is worthy of clinical promotion.
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Memo
基金项目：陕西省中医药管理局课题（2021-GJ-JG009）；陕西中医药大学科研基金项目（2020GP40）；陕西中医药大学附属医院科研基金项目（2020MS005）