[1] DU Yongbo YANG Jianwei WANG Meimei XU Xinsong WANG Hongjie,.Effectiveness of Fuyu Decoction in Treating Chronic Heart FailureBased on Cardiac Function and Oxidative Stress Indicators [J]. Modern Traditional Chinese Medicine, 2023, (05): 74-79. [doi: 10.13424/j.cnki.mtcm.2023.05.015]
Effectiveness of Fuyu Decoction in Treating Chronic Heart FailureBased on Cardiac Function and Oxidative Stress Indicators
- Article number:
- 1672-0571(2023)05-0074-06
- Keywords:
- Key words:Cardiac function; Chronic heart failure; Fuyu decoction; Oxidative stress; Randomized controlled
- ZTFLH:
- R256.2
- Code:
- A
- Abstract:
- Abstract：Objective To explore the effects of Fuyu decoction on heart function and oxidative stress indicators in patients with chronic heart failure.Methods 120 patients with chronic heart failure admitted to Hanzhong Central Hospital from January 2020 to January 2022 were collected and randomly divided into a control group (60 cases，treated with conventional Western medicine) and a treatment group (60 cases，treated with conventional Western medicine+Fuyu decoction).The therapeutic effect was evaluated，and the scores of traditional Chinese medicine symptoms before and after treatment were recorded.Cardiac function indicators and oxidative stress indicators were measured before and after treatment，and the occurrence of adverse reactions during treatment was recorded.Results The total effective rate of the treatment group was significantly higher than that of the control group (P<0.05)；After treatment，the main symptom score and secondary symptom score of the treatment group were significantly lower than those of the control group (P<0.05)；After treatment，the left ventricular end diastolic diameter (LVEDD)，left ventricular end systolic diameter (LVESD)，and serum malondialdehyde (MDA) levels in the treatment group were significantly lower than those in the control group (P<0.05)；The left ventricular ejection fraction (LVEF) and serum superoxide dismutase (SOD) levels were significantly higher than those in the control group (P<0.05)；There was no significant difference in the incidence of adverse reactions between groups (P>0.05).Conclusion Treating patients with chronic heart failure with Fuyu decoction can significantly lower the levels of oxidative stress indicators，improve clinical symptoms and heart function，enhance overall efficacy，and the combined treatment has high safety.
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Memo
基金项目：陕西省社会发展科技攻关项目（2016SF224）