[1] CHEN XinghuiXIE RuiLIU YaoZHANG JingkunLI PuJI Hua,.Therapeutic Effect of Jianpi Xiaowei Decoction Combined with Colloidal Pectin Bismuth Capsules on Chronic Atrophic Gastritis and Its Effects on Levels of Gastrin 17，Pepsinogen，and Inflammatory Factors [J]. Modern Traditional Chinese Medicine, 2024, (01): 74-78. [doi: 10.13424/j.cnki.mtcm.2024.01.016]
Therapeutic Effect of Jianpi Xiaowei Decoction Combined with Colloidal Pectin Bismuth Capsules on Chronic Atrophic Gastritis and Its Effects on Levels of Gastrin 17，Pepsinogen，and Inflammatory Factors
- Article number:
- 1672-0571(2024)01-0074-05
- Keywords:
- Key words:Chronic atrophic gastritis; Jianpi Xiaowei decoction; Colloidal pectin secret capsules; Gastrin-17; Pepsinogen
- ZTFLH:
- R256.3
- Code:
- A
- Abstract:
- Abstract：Objective To study the effects of Jianpi Xiaowei decoction combined with colloidal pectin bismuth capsules on the levels of gastrin-17 (G-17)，pepsinogen (PG)，and inflammatory factors in patients with chronic atrophic gastritis.Methods Eighty patients with chronic atrophic gastritis who came to our hospital for treatment from June 2019 to June 2022 were selected and randomly divided into a control group (40 cases，colloidal pectin bismuth capsules) and a treatment group (40 cases，colloidal pectin bismuth capsules+Jianpi Xiaowei decoction).Both groups were given basic treatment，and the therapeutic effect was evaluated.Serum inflammatory factors，PG，and GAS-17 levels were measured.Results The total effective rate of the treatment group was significantly higher than that of the control group (P＜0.05)；After treatment，the serum levels of interleukin-2(IL-2) and IL-6 in the treatment group were significantly lower than those in the control group (P＜0.05)；After treatment，the serum levels of PGI and G-17 in the treatment group were significantly higher than those in the control group，while the levels of PGII were significantly lower than those in the control group (P＜0.05).Conclusion The combination of Jianpi Xiaowei decoction and colloidal pectin secret capsules can alleviate inflammation，improve PG and G-17 levels，alleviate clinical symptoms in patients with chronic atrophic gastritis，and have a definite overall therapeutic effect.
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Memo
基金项目：陕西省中医药管理局基金项目（SZY-NLTL-2022-029）