[1] XIONG Mengting LI YingxiaXU Chao ZHANG Yuanbing WANG Kaisheng,.Effect of Yiqi Huatan Jiedu Anticancer Formula on theQuality of Life of Non-Small Cell Lung Cancer Patients [J]. Modern Traditional Chinese Medicine, 2024, (05): 67-72. [doi: 10.13424/j.cnki.mtcm.2024.05.013]
Effect of Yiqi Huatan Jiedu Anticancer Formula on theQuality of Life of Non-Small Cell Lung Cancer Patients
- Article number:
- 1672-0571(2024)04-0064-06
- Keywords:
- Key words:Non-small cell lung cancer; Yiqi Huatan Detoxification and Anti Cancer Formula; Traditional Chinese Medicine Syndrome; Qi deficiency; phlegm obstruction; and toxin accumulation syndrome; Quality of life
- ZTFLH:
- R256.19
- Code:
- A
- Abstract:
- Abstract：Objective To observe the effect of Yiqi Huatan Jiedu Anticancer Formula on the quality of life of patients with non-small cell lung cancer.Methods Patients who met the criteria were included and randomly divided into a treatment group and a control group，with 30 cases in each group.The control group was given the molecular targeted drug gefitinib tablets orally；The treatment group took a combination of Qi tonifying，phlegm resolving，detoxifying，and anti-cancer formula on the basis of the control group.Compare the efficacy of two groups of traditional Chinese medicine syndromes，changes in Karnofsky score，quality of life measurement scale scores，and the incidence and severity of common adverse reactions of targeted drugs.Results After treatment，the therapeutic effect of traditional Chinese medicine syndrome in the treatment group was significantly better than that in the control group (P<0.05).The mean score of Karnofsky in the treatment group increased，and there was a significant difference compared with the control group，with statistical significance (P<0.05).In the comparison of functional domains in the quality of life measurement scale，there were significant differences between the two groups in the physical domain and role domain (P<0.05)；Comparison of symptom subsets showed significant differences between the two groups in symptoms of fatigue，appetite，and diarrhea (P<0.05).There was a significant difference in the grading and incidence of adverse reactions between the two groups (P<0.05).Conclusion The formula for nourishing Qi，resolving phlegm，detoxifying，and fighting cancer can effectively improve the clinical symptoms of non-small cell lung cancer (Qi deficiency，phlegm obstruction，and toxin accumulation syndrome) patients，improve their quality of life，and is safe，reliable，and effective in reducing toxicity and increasing efficacy.
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Memo
基金项目：2022年度江西省卫生健康委科技计划项目（202210763）；中医肺科学江西省重点实验室（赣科发财字［2024］18号）