[1] Yuan Youcai Song Xuan Cao Yang,.Clinical Study of the Effect of Tiaozhi Ｒoumai Granules on Blood Lipid and Carotid Artery Intima of Symptomatic Carotid Atherosclerosis [J]. Modern Traditional Chinese Medicine, 2018, (05): 17-20. [doi: 10．13424/j．cnki．mtcm．2018．05．006]
Clinical Study of the Effect of Tiaozhi Ｒoumai Granules on Blood
Lipid and Carotid Artery Intima of Symptomatic Carotid Atherosclerosis
Modern Traditional Chinese Medicine[ISSN: 1006-6977/ CN: 61-1281/TN]
Volumes & Issues:
2018 05
pagination:
17-20
Column:
Publication date:
2018-09-15
- Article number:
- 1672－0571(2018)05－0017－04
- ZTFLH:
- Ｒ256. 2
- Code:
- A
- Abstract:
- To treat the effect of Tiaozhi Ｒoumai Granules on blood lipid and carotid artery intima of symptomatic carotid atherosclerosis． Method: 90 cases of carotid atherosclerosis were randomly divided into treatment group (60 cases) and control group (30 cases)． The control group was treated with Atorvastatin Calcium and Aspirin Enteric － coated Tablets，and the treatment group was treated with Tiaozhi Ｒoumai Granules on the basis of the control group． After 12 weeks，the blood lipids were measured and B － scan ultrasonography of the carotid arteries were applied in both groups． Ｒesult: IMT in bilateral carotid arteries was significantly lower than that before treatment (P ＜0． 05)，and there was no significant difference between the two groups (P ＞0． 05)． Carrouse scores of carotid atherosclerosis in both groups showed a downward trend after treatment，and there was no significant difference between the two groups (P ＞0． 05)． The improvement of TC and LDL － C in the treatment group was better than that in the control group，and the difference was statistically significant (P ＜0． 05)． Conclusion: Tiaozhi Ｒoumai Granules combined with Western medicine can reduce blood lipid levels in patients with carotid atherosclerosis and delay the development of carotid atherosclerosis．
References:
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[2]杨志宏，李经渭，袁有才，等． 调脂柔脉颗粒对高脂血症大鼠动脉壁 ICAM －1 基因表达的影响［J]． 陕西中医，2016，37(5):630 －631．
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[4]何文． 颈动脉彩色多普勒超声与临床［M]． 北京:科学技术文献出版社，2007:57 －58．
[5]潘利红． 阿托伐他汀钙治疗脑动脉硬化的临床效果分析［J]． 中国动脉硬化杂志，2014，22(7):711 －714．
[6]龙宜武，唐明，龙强，等． 脑心通胶囊联合阿托伐他汀钙对老年颈动脉粥样硬化斑块的影响［J]． 长春中医药大学学报，2014，30(1):109 －111．
Memo
收稿日期:2018 －05 －15 编辑:巩振东 ＊
＊ ＊
基金项目:陕西中医药大学校基金(14XKLX02);陕西中医药大学附院医院基础项目(2014K －28)
通讯作者:问莉娜(1981 － )，女，硕士，主治医师，研究方向:脑血管病的中医学防治。E － mail:welinapm@126． Com
Last Update:
2019-12-09