• 陕西省优秀期刊
  • 主办:陕西中医药大学

[1] LI liang CHEN Yucheng WANG Qiang ZHOU Jie,.Effect of Mahuang Fuzi Xixin Decoction on PI3K/Akt/mTOR Signal Pathway in Yang Deficiency Non-small Cell Lung Cancer Mice [J]. Modern Traditional Chinese Medicine, 2022, 1(02): 43-48. [doi: 10.13424/j.cnki.mtcm.2022.02.008]
Copy

Effect of Mahuang Fuzi Xixin Decoction on PI3K/Akt/mTOR Signal Pathway in Yang Deficiency Non-small Cell Lung Cancer Mice

References:

[1]陆颖,倪伟,赵晓霆,等.从阳虚论治肺积的文献整理及研究概况[J].中华中医药杂志,2019,34(1):291-294.
[2]Thorpe LM,Yuzugullu H,Zhao JJ.PI3K in cancer:divergent roles of isoforms,modes of activation and therapeutic targeting[J].Nature Reviews Cancer,2015,15(1):7-24.
[3]李亮,杜斌,周洁,等.王强主任以麻黄附子细辛汤治疗少阴里虚兼表证非小细胞肺癌思想探析[J].医学信息,2020,33(6):154-155.
[4]Bray F,Ferlay J,Soerjomataram I,et al.Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA:a Cancer Journal for Clinicians,2018,68(6):394-424.
[5]Cho JH.Immunotherapy for non-small-cell lung cancer:current status and future obstacles[J].Immune Network,2017,17(6):378-391.
[6]Okkenhaug K,Graupera M,Vanhaesebroeck B.Targeting PI3K in cancer:impact on tumor cells,their protective stroma,angiogenesis,and immunotherapy[J].Cancer Discovery,2016,6(10):1090-1105.
[7]Liao Y,Hung MC.Physiological regulation of Akt activity and stability[J].American Journal of Translational Research,2010,2(1):19-42.
[8]Díaz-Serrano A,Angulo B,Dominguez C,et al.Genomic profiling of HER2-positive gastric cancer:PI3K/Akt/mTOR pathway as predictor of outcomes in HER2-positive advanced gastric cancer treated with trastuzumab[J].The Oncologist,2018,23(9):1092-1102.
[9]Firat E,Niedermann G.FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition[J].Oncotarget,2016,7(34):54883-54896.
[10]Breitkopf SB,Yang XM,Begley MJ,et al.A cross-species study of PI3K protein-protein interactions reveals the direct interaction of P85 and SHP2[J].Scientific Reports,2016,6:20471.
[11]高胜东,戴蓉,周钊.LncRNA CRNDE激活PI3K/Akt通路促进非小细胞肺癌细胞增殖、迁移及侵袭[J].生物医学工程与临床,2021,25(1):85-91.
[12]吴昊,魏吉红,郑瑾,等.论阳虚与肿瘤形成的关系[J].中华中医药杂志,2017,32(3):969-971.
[13]张元兵,王丽华,李少峰,等.从阳虚痰凝流注论治肺腺癌初探[J].江西中医药,2020,51(10):11-13.
[14]李亮,周洁.浅谈阳虚和肿瘤[J].中医药信息,2012,29(6):6-7.
[15]李仲普,胡学军,冯磊,等.阳和汤抑制阳虚证小鼠Lewis肺癌生长的实验研究[J].中医药导报,2017,23(9):25-29.
[16]Feng HT,Zhao WW,Lu JJ,et al.Hypaconitine inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses adhesion,migration,and invasion of lung cancer A549 cells[J].Chinese Journal of Natural Medicines,2017,15(6):427-435.
[17]王楚慰.温阳附子汤治疗肺癌咳血患者的临床观察[J].深圳中西医结合杂志,2015,25(9):168-169.
[18]黄颖,周洁.周洁教授巧用温阳法治疗恶性肿瘤化疗副反应的经验[J].内蒙古中医药,2018,37(5):28-29.
[19]钦敬茹,徐祖红,王中奇.王中奇老师运用麻黄附子细辛汤治疗肺癌经验[J].吉林中医药,2018,38(4):402-404,408.
[20]杨露,谢晓芳,郑川,等.麻黄附子细辛汤联合紫杉醇诱导A549/T细胞凋亡的研究[J].中药药理与临床,2015,31(3):11-13.
[21]张梦凡.张林军运用桂枝去芍药加麻黄附子细辛汤加减治疗肿瘤的经验[J].中医临床研究,2020,12(24):3-5.
[22]朱芳.麻黄附子细辛汤治疗肺癌疼痛临床观察[J].中国中医药现代远程教育,2021,19(3):101-103.

Memo

基金项目:天津市教委科研计划项目(2019KJ069)

Last Update: 2022-04-08
Copyright @ 2020 Editorial Office of Modern Traditional Chinese Medicine
 Address: Middle Section of Century Avenue, Xianyang, Shaanxi Province. Post Code: 712046
Tel: 029-38185250 Fax: 029-38185250 E-mail: shxzhzs@163.com Powered by: www.editorhome.cn