[1] LIN Shunyan YIN Zhenglu SUN Chao CHEN Bo GAO Wei,.Application of Rapid Rehabilitation Surgery with Chinese characteristics in Elderly Patients with Lung Cancer Undergoing Thoracoscopic Radical Surgery [J]. Modern Traditional Chinese Medicine, 2023, (01): 110-115. [doi: 10.13424/j.cnki.mtcm.2023.01.021]
Application of Rapid Rehabilitation Surgery with Chinese characteristics in Elderly Patients with Lung Cancer Undergoing Thoracoscopic Radical Surgery
- Article number:
- 1672-0571(2023)01-0110-06
- Keywords:
- TCM; Rapid rehabilitation surgery; Lung cancer; Thoracoscope; Lung function; Inflammatory cytokine
- ZTFLH:
- R273?
- Code:
- A??
- Abstract:
- Objective To construct a rapid rehabilitation surgery with Chinese characteristics (ERAS) and evaluate its safety and effectiveness in elderly patients with lung cancer undergoing thoracoscopic radical surgery.Methods From January 1，2018 to December 31，2020，the elderly patients with lung cancer who underwent thoracoscopic radical surgery in Subei Peoples Hospital were prospectively selected and divided into the control group and the treatment group by random number table.The patients in the control group received ERAS treatment during the perioperative period，and the patients in the treatment group received ERAS treatment with Chinese characteristics.Postoperative complications，pulmonary function before and 3 days after operation and peripheral serum interleukin1β(IL1β)，Interleukin10 (IL10)，tumor necrosis factorα (TNFα) were compared between the two groups .Results A total of 70 lung cancer patients met the inclusion criteria in this study，and 67 patients completed the study，including the control group (n=23) and the treatment group (n=34).The extubation time，ambulation time and hospitalization time of the control group were (5.31±1.17)，(3.14±1.02) and (8.69±1.37) days，respectively；The treatment group was (3.12±1.11)，(2.08±0.75) and (6.57±1.25) days，respectively.The indexes in the treatment group were better than those in the control group，with a statistically significant difference (P<0.05).There were 11 cases of complications in the control group (33.3%)，and 6 cases in the treatment group (17.6%).The incidence in the treatment group was lower than that in the control group，with a statistically significant difference (P<0.05).The pulmonary function indexes of the two groups decreased one day before discharge，with statistical significance (P<0.05).Compared with the control group，the treatment group was superior to the control group，with statistical significance (P<0.05).Three days after operation，all indexes of the two groups were higher than before，and the difference was statistically significant (P<0.05).Compared between groups，all indexes of the treatment group were lower than those of the control group，and the difference was statistically significant (P<0.05). Conclusion ERAS system with Chinese characteristics can reduce the complications of elderly patients with lung cancer after thoracoscopic radical surgery，which is conducive to the recovery of lung function and inhibits the release of early inflammatory factors.
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Memo
基金项目：江苏省青年医学重点人才项目（QNRC2016336）；扬州市医学重点人才项目（201847）