[1] YIN LiHUANG JuyunLU ChengshuJIANG Deqi?ZENG ShiyuanWANG Huakun,.Application of Multi Omics Integration Strategy in Study of Antidepressant Mechanisms in Traditional Chinese Medicine [J]. Modern Traditional Chinese Medicine, 2024, (02): 1-7. [doi: 10.13424/j.cnki.mtcm.2024.02.001]
Application of Multi Omics Integration Strategy in Study of Antidepressant Mechanisms in Traditional Chinese Medicine
- Article number:
- 1672-0571(2024)02-0001-07
- Keywords:
- Key words:Multi omics; Mechanism of action; Traditional Chinese medicine; Anti depression; Integration technology
- ZTFLH:
- R277.7
- Code:
- A
- Abstract:
- Abstract：Depression is a common mental and psychological disorder with a complex pathogenesis.Traditional Chinese medicine has unique advantages in treating depression based on syndrome differentiation and treatment，which vary from person to person and from disease to disease.With the rapid development of molecular biology technology，multi omics techniques have been widely applied in the analysis of the antidepressant effects of effective ingredients in traditional Chinese medicine.The article systematically introduces the core technologies of multi omics，with a focus on summarizing the ideas，methods，and progress of genomics，proteomics，transcriptomics，metabolomics，and multi omics integration technologies in the study of the mechanism of antidepressant effects of traditional Chinese medicine in recent years，providing reference for promoting the application of multi omics technologies in the treatment of depression with traditional Chinese medicine.
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Memo
基金项目：国家自然科学基金项目(81960658)；广西高校中青年教师科研基础能力提升项目(2021KY0584)；玉林师范学院高层次人才科研启动项目(G2018027)