[1]郭小兰 姚洁 董博.补肾益气中药对膝骨性关节炎患者生存质量的影响[J].现代中医药,2018,(06):051-53.[doi:10.13424/j.cnki.mtcm.2018.06.018]
　Guo Xiaolan Yao Jie Dong Bo.Effect of Chinese Medicine for Invigorating Kidney and Boosting Qi on the Quality of Life of Patients with Knee Osteoarthritis[J].Modern Traditional Chinese Medicine,2018,(06):051-53.[doi:10.13424/j.cnki.mtcm.2018.06.018]
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补肾益气中药对膝骨性关节炎患者生存质量的影响()
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2018年06期
页码:
051-53
栏目:
临床研究
出版日期:
2018-11-18

文章信息/Info

Title:
Effect of Chinese Medicine for Invigorating Kidney and Boosting Qi on the Quality of Life of Patients with Knee Osteoarthritis
文章编号:
1672－0571(2018)06－0051－04
作者:
郭小兰 1 姚洁 1 董博 2
1.陕西中医药大学，陕西 咸阳 ７１２０４６；2.陕西中医药大学附属医院，陕西 咸阳 ７１２０００
Author(s):
Guo Xiaolan 1 Yao Jie 1 Dong Bo 2
1． Shaanxi University of Chinese Medicine，Xianyang China，712046; 2． Affiliated Hospital of Shaanxi University of Chinese Medicine，Xianyang China，712000
关键词:
膝骨性关节炎; 补肾益气法; 中药治疗; 生存质量
Keywords:
knee osteoarthritis;  method of invigorating kidney and boosting Qi;  Chinese medicine treatment;  quali- ty of life
分类号:
R684. 3
DOI:
10.13424/j.cnki.mtcm.2018.06.018
文献标志码:
B
摘要:
目的 观察补肾益气中药对膝骨性关节患者生存质量的影响，从而评价其治疗效果。方法 按照随 机原则将 ８０例膝骨性关节患者分为中药组和西药组各 ４０例，中药组给予补肾益气中药口服，西药组给予西乐 葆口服，疗程 ４周，用 ＳＦ－３６生存质量调查问卷对患者治疗前后健康状况进行调查并评价。结果 两组患者进 行生存质量比较，治疗前所有项目差异均无统计学意义（Ｐ＞０．０５），具有可比性；治疗后在生理功能 ＰＦ、躯体疼 痛 ＢＰ方面比较，差异无统计学意义（Ｐ＞０．０５），但在生理职能 ＲＰ、总体健康 ＧＨ、活力 ＶＴ、社
Abstract:
To evaluate the therapeutic effect of traditional Chinese medicine for invigorating kidney and boosting Qi on the quality of life of patients with knee osteoarthritis． Method: 80 patients with knee osteoarthritis were randomly divided into the traditional Chinese medicine group and the western medicine group，with 40 cases in each． The traditional Chinese medicine group was given orally Chinese medicine invigorating kidney and boosting qi，and the western medicine group was given orally Cele- brex，both for 4 weeks． The health status of the patients before and after treatment was investigated and evaluated by SF －36 quality of life questionnaire． Result: The quality of life was compared between the two groups． There was no significant difference in all items before treatment (P ＞ 0． 05)，which was comparable． There was no significant difference in PF and BP after treatment (P ＞0． 05)． )，but in RP，GH，VT，SF，RE，MH，the Chinese medicine group was significantly higher than those in the western medicine group，the difference was statistically significant (P ＜0． 05)． Conclusion: Kidney － in- vigorating and Qi － boosting herbs can obviously improve the quality of life of patients with knee osteoar-thritis and have reliable curative effect on knee osteoarthritis．

参考文献/References:

[1]中华医学会骨科分会．骨关节炎诊治指南（２００７版） ［Ｊ]．中华骨科杂志，２００７，２７（１０）：７９３－７９６．
[2]郑筱萸．中华人民共和国国家药品监督管理局．中药新 药临床研究指导原则［Ｍ]．北京：中国医药科技出版 社，２００２：３５６－３６０．
[3]ＷｅｒｅＪＥ，ＫｏｓｉｎｓｋｉＭ，Ｈａｔｏｕｍ ＨＴ，ｅｔａｌ．ＩｓｔｈｅＳＦ－３６ ｈｅａｌｔｈＳｕｒｖｅｙａｖａｌｉｄｍｅａｓｕｒｅｏｆｏｓｔｅｏａｒｔｈｒｉｔｉｓａｎｄｒｈｅｕ ｍａｔｏｉｄａｒｔｈｒｉｔｉｓ．［Ｊ]ＡｒｔｈｒｉｔｉｓＲｈｅｕｍＳ２５８，１９９６．
[4]邢秋娟，吴佶，戴薇薇，等．益气化瘀补肾方治疗早中期 原发性膝骨关节炎临床研究［Ｊ]．河南中医，２０１８，３８ （３）：３９６－４０３．
[5]王之海，秦辉东，徐科，等．中医综合治疗 ３０例慢性骨 关节 炎 临 床 体 会 ［Ｊ]．中 国 保 健 营 养，２０１６，２６ （８）：１６０．
[6]王晓冰．中医药治疗膝骨关节炎［Ｊ]．实用中医内科杂 志，２０１５，２９（７）：１６７－１６８．
[7]董博，李永志，袁普卫，等．李堪印治疗膝骨性关节炎经 验［Ｊ]．河南中医，２０１４，３４（２）：２１７－２１８
[8]ＹＵＡＮＰｕｗｅｉ，ＬＩＵＤｅｙｕ，ＣＨＵＸｉａｎｇｄｏｎｇ，ｅｔａｌ．Ｅｆｆｅｃｔ ｓｏｆＰｒｅｖｅｎｔｉｖｅＡｄｍｉｎｉｓｔｒａｔｉｏｎｏｆＪｕａｎｂｉＣａｐｓｕｌｅｓｏｎＴＮＦ －α，ＩＬ－１ＡｎｄＩＬ－６ＣｏｎｔｅｎｔｓｏｆＪｏｉｎｔＦｌｕｉｄｉｎｔｈｅＲａｂｂｉｔ ｗｉｔｈＫｎｅｅＯｓｔｅｏａｒｔｈｒｉｔｉｓ［Ｊ]．ＪｏｕｒｎａｌｏｆＴｒａｄｉｔｉｏｎａｌＣｈｉ ｎｅｓｅＭｅｄｉｃｉｎｅ，２０１０，３０（４）：２５４－２５８．
[9]ＹＵＡＮ Ｐｕｗｅｉ，ＹＵ Ｈｏｎｇｃｈａｏ，ＺＨＯＵ Ｈａｉｚｈｅ，ｅｔａｌ． ＥｆｆｅｃｔｓｏｆＰｒｅｖｅｎｔｉｖｅＡｄｍｉｎｉｓｔｒａｔｉｏｎｏｆＪｕａｎｂｉＣａｐｓｕｌｅｓｏｎ ＥｘｐｒｅｓｓｉｏｎｓｏｆＳｅｒｕｍＭＭＰ－２ａｎｄＭＭＰ－９ａｎｄＨｉｓｔｏ ｌｏｇｉｃａｌＣｈａｎｇｅｓｏｆＣａｒｔｉｌａｇｅｉｎｔｈｅＲａｂｂｉｔｏｆＫｎｅｅＯｓｔｅｏａｒ ｔｈｒｉｔｉｓ［Ｊ]．ＪｏｕｒｎａｌｏｆＴｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅＭｅｄｉｃｉｎｅ，２０１１， ３１（４）：１８２－１８４．
[1０]康武林，袁普卫，张根印，等．补肾益气法中药预防用 药对膝骨性关节炎家兔血清中 ＡＱＰ１及 ＡＱＰ３表达的 影响［Ｊ]．四川中医，２０１４，３２（１１）：３２－３５．
[1１]ＰＵＬＪＡＫＬ，ＭＡＲＩＮＡ，ＶＲＤＯＬＪＡＫＤ，ｅｔａｌ．Ｃｅｌｅｃｏｘｉｂ ｆｏｒｏｓｔｅｏ－ａｒｔｈｒｉｔｉｓ［Ｊ]．ＣｏｃｈｒａｎｅＤａｔａｂａｓｅＳｙｓｔＲｅｖ， ２０１７，２２（５）：１９８－２０５．
[1２]ＫＲＡＵＳＭＡ，ＦＬＵＣＫＲＪ，ＷＥＩＮＨＡＮＤＥＤ，ｅｔａｌ．Ｉｎｔｅｎ ｓｉｖｅＨｅｍｏ－ｄｉａｌｙｓｉｓａｎｄＨｅａｌｔｈ－ＲｅｌａｔｅｄＱｕａ

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备注/Memo

备注/Memo:
收稿日期:2018 －04 －13 编辑:杨芳艳*
基金项目:陕西省科技厅自然基础项目(2018JM132)
更新日期/Last Update: 2019-12-09