[1]吴爽 常鹏程 岳晓峰 周志焕.方剂配伍信息挖掘系统的构建及惊悸古方配伍规律分析[J].现代中医药,2022,1(03):037-42.[doi:10.13424/j.cnki.mtcm.2022.03.007]
　WU Shuang CHANG Pengcheng YUE Xiaofeng ZHOU Zhihuan.Construction of Prescription Compatibility Information Mining System and Analysis of Compatibility Law of Palpitation Ancient Prescription[J].Modern Traditional Chinese Medicine,2022,1(03):037-42.[doi:10.13424/j.cnki.mtcm.2022.03.007]
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方剂配伍信息挖掘系统的构建及惊悸古方配伍规律分析
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
1
期数:
2022年03期
页码:
037-42
栏目:
方药纵横
出版日期:
2022-06-10

文章信息/Info

Title:
Construction of Prescription Compatibility Information Mining System and Analysis of Compatibility Law of Palpitation Ancient Prescription
文章编号:
1672-0571(2022)03-0037-06
作者:
吴爽 常鹏程 岳晓峰 周志焕
天津中医药大学，天津 300193
Author(s):
WU Shuang CHANG Pengcheng YUE Xiaofeng ZHOU Zhihuan
1.School of Traditional Chinese Medicine，Tianjin University of Traditional Chinese Medicine，Tianjin 300193,China；
2.Graduate School，Tianjin University of Traditional Chinese Medicine，Tianjin 300193,China
关键词:
关键词：中医药; 方剂; 挖掘系统; 惊悸; 配伍规律
Keywords:
Key words：Traditional Chinese medicine; Prescription; Excavation system; Palpitation; Compatibility law
分类号:
R289.1
DOI:
10.13424/j.cnki.mtcm.2022.03.007
文献标志码:
A
摘要:
摘 要：目的 构建方剂配伍信息综合挖掘系统并分析治疗惊悸古方组方配伍规律。方法 对《中医方剂大辞典》《中华医典》中有关治疗惊悸的方剂进行收集整理，并将所得信息进行标准化处理，建立方剂配伍信息综合挖掘系统，通过数据挖掘方法和文献计量学方法对组方配伍规律、剂型和证型等进行分析。结果 ①惊悸古方以宋代方剂占比最高，其次为明、清方剂。②惊悸古方剂型，丸剂最多，其次为汤剂、散剂、酒剂。③在收集的 233首惊悸古方中，以人参的出现频数最高，其次为甘草、远志、茯神、茯苓、麦冬、朱砂、当归、酸枣仁、石菖蒲、白术、龙齿、防风等，其中以补益药与安神药为多。④惊悸古方常用药对分析，人参-远志、人参-茯神为方中出现频数最高的药对配伍。⑤关联规则分析显示，(远志-茯神)-＞人参、(麦冬-甘草)-＞人参、(甘草-茯神)-＞人参为置信度大于0.80的配伍。⑥惊悸证型以虚实夹杂证为主。结论 通过治疗惊悸古方组方配伍分析，为临床辨证论治惊悸提供一定参考依据。
Abstract:
Abstract：Objective To construct a comprehensive mining system of prescription compatibility information and analyze the compatibility law of ancient prescriptions for the treatment of palpitation.Methods The prescriptions for the treatment of palpitation in the Dictionary of Traditional Chinese Medicine Prescriptions and Zhong Hua Yi Dian were collected and sorted out，and the obtained information was standardized.A comprehensive mining system for prescription compatibility information was established.The compatibility law，dosage form and syndrome type of prescriptions were analyzed by data mining and bibliometric methods.Results ① Song Dynasty prescriptions accounted for the highest proportion of palpitation ancient prescriptions，followed by Ming and Qing prescriptions.② The dosage form of palpitation ancient prescription is pill，followed by decoction，powder and wine.③ Among the 233 ancient prescriptions collected，Ginseng has the highest frequency，followed by Licorice，Polygala tenuifolia，Poria，Poria cocos，Ophiopogon japonicus，Cinnabar，Angelica sinensis，Wild jujube kernel，Acorus calamus，Atractylodes macrocephala，Longchi and Fangfeng，among which tonic drugs and tranquilizing drugs are the most；④ According to the analysis of common drug pairs in palpitation ancient prescription，Ginseng-Polygala tenuifolia and Ginseng-Fushen are the most frequent drug pairs；⑤ Association rule analysis showed that，(Polygala tenuifolia - Fushen) - ＞Ginseng，(Ophiopogon japonicus - Licorice) -＞Ginseng，(Licorice - Fushen) -＞Ginseng were compatibility with confidence greater than 0.80；⑥ Palpitation syndrome type is mainly mixed with deficiency and excess syndrome.Conclusion The compatibility analysis of ancient prescriptions for the treatment of palpitation can provide a certain reference basis for the clinical treatment of palpitation based on syndrome differentiation.

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备注/Memo

备注/Memo:
基金项目：国家973项目（2012CB518401）
更新日期/Last Update: 2022-05-30