[1]刘岳张朝驹何川李孝林刘道东陈洪卫彭昌华王华东.舒筋止眩汤联合盐酸氟桂利嗪治疗颈源性眩晕痰湿阻络证临床研究[J].现代中医药,2024,(03):052-57.[doi:10.13424/j.cnki.mtcm.2024.03.010]
 LIU YueZHANG ChaojuHE ChuanLI XiaolinLIU DaodongCHEN HongweiPENG ChanghuaWANG Huadong.Clinical Study on Combination of Shujin Zhixuan Decoction andFlunarizine Hydrochloride in the Treatment of CervicalVertigo with Phlegm Dampness Obstruction Syndrome[J].Modern Traditional Chinese Medicine,2024,(03):052-57.[doi:10.13424/j.cnki.mtcm.2024.03.010]
点击复制

舒筋止眩汤联合盐酸氟桂利嗪治疗颈源性眩晕痰湿阻络证临床研究()
分享到:

《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2024年03期
页码:
052-57
栏目:
出版日期:
2024-05-20

文章信息/Info

Title:
Clinical Study on Combination of Shujin Zhixuan Decoction andFlunarizine Hydrochloride in the Treatment of CervicalVertigo with Phlegm Dampness Obstruction Syndrome
文章编号:
1672-0571(2024)03-0052-07
作者:
刘岳1张朝驹2何川2李孝林2刘道东2陈洪卫2彭昌华2王华东2
1.湖北中医药大学,湖北 武汉 430000;
2.湖北中医药大学附属荆州市中医医院,湖北 荆州 434000
Author(s):
LIU Yue1ZHANG Chaoju2HE Chuan2LI Xiaolin2LIU Daodong2CHEN Hongwei2PENG Changhua2WANG Huadong2
1.Hubei University of Chinese Medicine,Wuhan 430000,China;
2.Jingzhou ChineseMedicine Hospital Affiliated with Hubei University of Chinese Medicine,Hubei Jingzhou 434000,China
关键词:
关键词:颈源性眩晕舒筋止眩汤盐酸氟桂利嗪痰湿阻络证
Keywords:
Key words:Cervical vertigoShujin Zhixuan decoctionFlunarizine HydrochloridePhlegm dampness obstructing collaterals syndrome
分类号:
R255.3
DOI:
10.13424/j.cnki.mtcm.2024.03.010
文献标志码:
A
摘要:
摘要:目的 观察舒筋止眩汤联合盐酸氟桂利嗪治疗颈源性眩晕痰湿阻络证的临床效果。方法 随机将60例颈性眩晕病人分为治疗组与对照组,两组各30例;治疗组口服舒筋止眩汤联合盐酸氟桂利嗪胶囊治疗,对照组口服盐酸氟桂利嗪胶囊治疗,疗程2 w,并比较两组患者的治疗效果及治疗前后血液流变学与血流动力学的变化情况。结果 治疗组的总有效率为86.67%,明显优于对照组的63.33%,差异有统计学意义(P<0.05);治疗后,两组的血液流变学指标(全血高切黏度、血浆黏度、红细胞压积、全血低切黏度)、血流动力学指标(椎-基底动脉平均血流速度)均较治疗前有所改善,且治疗组各指标均优于对照组,差异有统计学意义(P<0.05);治疗过程中,两组患者未出现明显心慌胸闷、恶心呕吐、腹痛腹泻或眩晕症状加重等不良反应。结论 舒筋止眩汤联合盐酸氟桂利嗪胶囊治疗颈性眩晕更有优势,能有效降低血液黏度及改善血液循环,促进脑部供血,进而改善眩晕、上肢麻木、颈项僵硬疼痛等症状。
Abstract:
Abstract:Objective To explore the clinical effect of Shujin Zhixuan decoction combined with Flunarizine Hydrochloride in the treatment of cervical vertigo with phlegm dampness obstruction syndrome.Methods Sixty patients with cervical vertigo were randomly divided into a treatment group and a control group,with 30 cases in each group;The treatment group received oral administration of Shujin Zhixuan decoction combined with Flunarizine Hydrochloride capsules for treatment,while the control group received oral administration of Flunarizine Hydrochloride capsules for treatment for 2 weeks.The treatment effects and changes in blood rheology and hemodynamics before and after treatment were compared between the two groups of patients.Results The total effective rate of the treatment group was 86.67%,significantly better than the control groups 63.33%,with a statistically significant difference (P<0.05);After treatment,the hemorheological indicators (whole blood high shear viscosity,plasma viscosity,hematocrit,whole blood low shear viscosity) and hemodynamic indicators (vertebral basilar artery average blood flow velocity) of both groups improved compared to before treatment,and the treatment group had better indicators than the control group,with statistical significance (P<005);During the treatment,both groups of patients did not experience significant adverse reactions such as palpitations,chest tightness,nausea and vomiting,abdominal pain,diarrhea,or worsening symptoms of dizziness.Conclusion The combination of Shujin Zhixuan decoction and Flunarizine Hydrochloride capsules has more advantages in treating cervical vertigo.It can effectively reduce blood viscosity and improve blood circulation,promote cerebral blood supply,and thereby improve symptoms such as dizziness,upper limb numbness,and neck stiffness and pain.

参考文献/References:

[1]朱立国,李金学.脊柱骨伤科学[M].北京:人民卫生出版社,2015:183.
[2]孔令忠,纪清.颈性眩晕的发病学研究进展[J].湖北中医药大学学报,2013,15(4):62-64.
[3]赵胜杰,赵文娟,罗桂华,等.针刺疗法及八段锦为主的运动处方干预颈型颈椎病临床研究[J].现代中医药,2023,43(3):71-75.
[4]徐西林,张晓峰,胡海,等.张晓峰教授手法治疗颈性眩晕的经验总结[J].中国中医骨伤科杂志, 2020, 28(9):79-82.
[5]陈俊伟,谭志.龙氏徒手及牵引下正骨联合针刀治疗颈性眩晕临床研究[J].现代中医药,2022,42(4):139-143.
[6]颜明辉,戚欣生,宋清扬等.鍉圆针系统痧疗术治疗肝火上炎型后循环缺血性眩晕临床研究[J].现代中医药,2023,43(06):49-53.
[7]中华医学会.临床诊疗指南-骨科分册[M].北京:人民卫生出版社,2009:107.
[8]国家中医管理局.中医病症诊断标准[S].北京:中国中医药出版社,2018:37.
[9]陈琳.定眩汤治疗椎动脉型颈椎病临床疗效观察[D].北京:北京中医药大学,2020.
[10]谭依立,吕振,洪毅.颈性眩晕的研究进展[J].中国脊柱脊髓杂志,2022,32(7):648-653.
[11]王登杰,殷红兰,陈红艳,等.盐酸氟桂利嗪在前庭性偏头痛预防性治疗中的疗效及安全性[J].实用临床医药杂志,2020,24(5):76-78,81.
[12]吴连宝.西比灵联合地巴唑治疗血管神经性头痛的临床疗效观察[J].中国现代药物应用,2023,17(8):112-114.
[13]黄立莉,陈泽林,钟红英,等.中医药治疗颈性眩晕的研究进展[J].中医临床研究,2018,10(18):39-41.
[14]李印珊.补中益气汤化裁方治疗CSA眩晕的疗效分析[J].现代中医药,2020,40(3):57-60,64.
[15]赵丹.针刺配合刺血拔罐治疗颈性眩晕(风阳上扰型)的临床研究[D].长春:长春中医药大学,2020.
[16]徐马丽.罗氏勾点法治疗颈椎失稳引起的颈性眩晕的临床研究[D].成都:成都中医药大学,2020.
[17]申艳方,李卫萍,杜菊梅,等.银杏酮酯滴丸治疗脑动脉硬化症引起的眩晕临床研究[J].现代中医药,2022,42(5):107-110.
[18]黄泽,胡跃强,陈莲梅,等.血府逐瘀汤治疗眩晕病研究进展[J].陕西中医,2020,41(8):1169-1172.
[19]魏凯,王春丽.“调理脾胃”针法联合风池穴针刺治疗颈性眩晕的疗效及对椎-基底动脉血流动力学影响[J].针灸临床杂志,2020,36(6):15-18.
[20]张静,何勇,朱瑞,等.自拟定眩通络汤联合养血清脑颗粒治疗颈性眩晕的疗效及椎动脉血流动力影响观察[J].湖南师范大学学报(医学版),2020,17(3):101-104.
[21]王啸天,彭学锋,史圣华.葛根桂枝汤加减治疗颈椎病118例临床观察[J].内蒙古中医药,2016,35(1):44-45.
[22]赵颖.桂枝葛根汤加减配合微针强通首尾穴治疗颈椎病疗效观察[J].现代中西医结合杂志,2019,28(22):2485-2488.
[23]魏富芹,黄蓉,何海艳,等.天麻的药理作用及应用研究进展[J].中国民族民间医药,2021,30(11):72-76.
[24]柳威,邓林华,祁东利,等.天麻及其有效成分的药理作用概述[J].中药药理与临床,2021,37(4):240-244,12.
[25]王茹,王培利,王承龙.基于网络药理学研究人参调节能量代谢的作用机制[J].中华中医药学刊,2021,39(10):90-93,273-274.
[26]蔡金涛,李华刚.川芎-赤芍治疗下肢动脉硬化闭塞症的网络药理学机制[J].中医药临床杂志,2023,35(2):288-293.
[27]蔡扬帆,翁婧,林坤山,等.《伤寒论》葛根汤类方临床应用总结[J].国医论坛,2020,35(5):67-70.
[28]吴国庆,李志刚,杨佳一,等.葛根素的抗炎作用及其对神经系统疾病影响的研究进展[J].中西医结合心脑血管病杂志,2023,21(10):1807-1810.
[29]史晨旭,杜佳蓉,吴威,等.葛根化学成分及药理作用研究进展[J].中国现代中药,2021,23(12):2177-2195.
[30]董永丽,白子兴,高云,等.基于网络药理学的桂枝加葛根汤治疗颈椎病作用机制研究[J].世界中西医结合杂志,2020,15(7):1215-1219,1226.
[31]吕晓明,宋囡,王群,等.基于网络药理学探讨桂枝加葛根汤防治血脂异常的机制研究及实验验证[J].世界科学技术-中医药现代化,2021,23(11):3932-3940.

备注/Memo

备注/Memo:
基金项目:2022年全国名老中医药专家传承工作室建设项目(国中医药人教函〔2022〕75号)
更新日期/Last Update: 2024-05-20