[1]李永丰 林丽 薛思梦 乔海法.结肠运动与离子通道的研究进展*[J].现代中医药,2024,(06):024-29.[doi:10.13424/j.cnki.mtcm.2024.06.005]
　LI Yongfeng LIN Li XUE Simeng QIAO Haifa.Research Progress on Colonic Motility and Ion Channels[J].Modern Traditional Chinese Medicine,2024,(06):024-29.[doi:10.13424/j.cnki.mtcm.2024.06.005]
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结肠运动与离子通道的研究进展*()
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2024年06期
页码:
024-29
栏目:
出版日期:
2024-11-20

文章信息/Info

Title:
Research Progress on Colonic Motility and Ion Channels
文章编号:
1672-0571(2024)04-0026-05
作者:
李永丰 林丽 薛思梦 乔海法
陕西中医药大学针灸推拿学院针药结合创新中心，陕西 咸阳 712046
Author(s):
LI Yongfeng LIN Li XUE Simeng QIAO Haifa
Innovation Center for Combination of Acupuncture and Medicine, School of Acupuncture and Moxibustion and Massage,Shaanxi University of Chinese Medicine, Shaanxi Xianyang 712046,China
关键词:
关键词：结肠运动; 钙离子通道; 钾离子通道; 钠离子通道; TRPV1
Keywords:
Key words:Colonic motility;  Calcium ion channel;  Potassium ion channel;  Sodium ion channel;  TRPV1
分类号:
R574.62
DOI:
10.13424/j.cnki.mtcm.2024.06.005
文献标志码:
A
摘要:
摘 要：结肠运动障碍是导致肠道疾病的重要因素，且也常并发于其他器质性疾病。离子通道作为细胞膜上的一种跨膜受体蛋白，可介导离子被动流入/流出细胞，控制细胞质/细胞器内离子浓度、膜电位和细胞体积，是调控结肠运动的关键因素。文章围绕结肠运动与Ca2+、Na+、K+、TRPV1离子通道关系进行综述，可能为高效治疗结肠疾病提供研究基础。
Abstract:
Abstract：Colonic motility disorders are an important factor leading to intestinal diseases and are often associated with other organic diseases. As a transmembrane receptor protein on the cell membrane, ion channels can mediate the passive influx/efflux of ions into/from cells, control ion concentration, membrane potential, and cell volume in the cytoplasm/organelles, and are key factors in regulating colonic motility. The article reviews the relationship between colon motility and Ca2+, Na+, K+, TRPV1 ion channels, which may provide a research basis for efficient treatment of colon diseases.

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备注/Memo

备注/Memo:
基金项目：陕西省教育厅项目(20JK0592)
更新日期/Last Update: 2024-11-21