[1]陈 斌,赵红利.六君子汤合丹参饮治疗气虚血瘀证冠心临床研究[J].现代中医药,2019,(03):042-45.[doi:10.13424/j.cnki.mtcm.2019.03.014]
 Chen Bin Zhao Hongli.Effect of Liujunzi Decoction and Danshen Decoction on Patients with Coronary Heart Disease with Qi Deficiency and Blood Stasis Syndrome[J].Modern Traditional Chinese Medicine,2019,(03):042-45.[doi:10.13424/j.cnki.mtcm.2019.03.014]
点击复制

六君子汤合丹参饮治疗气虚血瘀证冠心临床研究()
分享到:

《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2019年03期
页码:
042-45
栏目:
临床研究
出版日期:
2019-05-30

文章信息/Info

Title:
Effect of Liujunzi Decoction and Danshen Decoction on Patients with Coronary Heart Disease with Qi Deficiency and Blood Stasis Syndrome
文章编号:
1672-0571(2019)03-0042-04
作者:
陈 斌赵红利
1.榆林市榆阳区中医医院?榆阳区青山路社区卫生服务中心,陕西榆林719000; 2.西安市新城区东郊第一职工医院,陕西西安710038
Author(s):
Chen Bin 1 Zhao Hongli 2
1. Yulin District TCM Hospital of Yulin, Community Health Service Center in Qingshan Road of Yuyang District, Yulin China, 719000; 2. First Staff Hospital of Xincheng District in Xi’ an, Xi’ an China, 710038
关键词:
冠心病六君子汤介入治疗支架气虚血瘀
Keywords:
coronary heart disease Liujunzi Decoction interventional therapy stent Qi deficiency and blood stasis
分类号:
R256.22
DOI:
10.13424/j.cnki.mtcm.2019.03.014
文献标志码:
A
摘要:
目的分析探讨六君子汤合丹参饮对气虚血瘀证冠心病患者经皮冠状动脉介入治疗术后支架内再狭窄的影响?方法选取我院于2015年1月~2017年1月期间收治的95例气虚血瘀证冠心病患者,按照随机数字表法将所有患者随机分为对照组和治疗组两组,所有患者均采取经皮冠状动脉介入术进行治疗,其中对照组患者均给予硝酸酯类?他汀类?阿司匹林?氯吡格雷等药物进行治疗,而治疗组患者则在此基础上联合使用六君子汤合丹参饮进行治疗,所有患者均持续治疗3个月?记录两组患者治疗前后的气虚积分和证候积分?支架再狭窄率以及血瘀积分等指标,比较两组
Abstract:
To explore the effect of Liujunzi Decoction and Danshen Decoction on in - stent restenosis in patients with coronary heart disease( CHD) with Qi deficiency and blood stasis syndrome after percutaneous coronary intervention. Methods: 95 patients with Qi deficiency and blood stasis syndrome who were admitted to our hospital from January 2015 to January 2017 were randomly divided into control group and treatment group according to random number table. All patients were treated by percutaneous coronary intervention. The control group was treated with nitrate esters,statins, aspirin and clopidogrel. On this basis, the patients in the treatment group were treated with Liujunzi Decoction and Danshen Decoction. All patients were treated for 3 months. The scores of Qi deficiency and syndrome, restenosis rate of stent and blood stasis before and after treatment were recorded, and the clinical effects of the two groups were compared. Results: There was no significant difference in TCM syndrome score, Qi deficiency syndrome score and blood stasis syndrome score between the two groups before treatment ( all P > 0. 05) ; TCM syndrome score and blood stasis syndrome score of the two groups after treatment were significantly better than those before treatment ( all O < 0. 05) ; Qi deficiency syndrome score of the treatment group after treatment was significantly better than that before treatment, and TCM syndrome and blood stasis syndrome of the treatment group after treatment were significantly better than those of the control group in the same period ( all P < 0. 05) . The restenosis rate in the treatment group was 4. 17%, which was significantly lower than that in the control group ( 19. 15% ( 2 = 9. 374, P < 0. 05) . The total effective rate of the treatment group was 95. 83%, which was significantly higher than 87. 23% of the control group ( 2 = 11. 444, P < 0. 05) . Conclusion: Liujunzi Decoction combined with Danshen Decoction can effectively improve in - stent restenosis in patients with coronary heart disease with Qi deficiency and blood stasis syndrome after percutaneous coronary intervention. The therapeutic effect is remarkable, and it is worthy of clinical application.

参考文献/References:

[1]赵宗磊,杜松,罗萍,等.益气活血法治疗不稳定型心绞痛PCI术后支架内再狭窄临床研究[J].中医学报,2017,32(11):2200-2203.
[2] Waldmann V, Laredo M, Nigam A, et al. Cyclical sinusbradycardia and atrioventricular block induced by ticagrelor[ J] . HeartRhythm Case Rep, 2018, 4( 11) : 527-529.
[3]仇卫锋,刘佳,向宗兴,等.加味丹参饮对冠心病血管内皮细胞损伤后细胞形态学的影响[J].陕西中医,2016,37(8):1042-1043.
[4] Liu Q, Fan J, Bai J, et al. IL - 34 promotes foam cellformation by enhancing CD36 expression through p38MAPK pathway[ J] . Sci Rep, 2018,8( 1) :17347.
[5]陈浩,邓悦.冠心病心绞痛代谢组学的证候客观化研究[J].世界科学技术-中医药现代化,2017,19(5):797-803.
[6] Fishman SL, Sonmez H, Basman C, et al. The role of advanced glycation end - products in the development of coronary artery disease in patients with and without diabetesmellitus: a review[ J] . Mol Med, 2018,24( 1) :59.
[7]杨威,宁微,李滕等.养心氏片治疗气虚血瘀型冠心病PCI术后心绞痛的临床观察[J].世界中医药,2018,13(3):614-615. [ 8] Sani CM, EPL P, Hrabia JB, et al. Association betweenlow - grade chronic inflammation and depressed left atrialcompliance in heart failure with preserved ejection fraction: A retrospective analysis [ J] . Folia Med Cracov,2018,58( 2) :45 -55.
[9]Sunyecz IL, McCallinhart PE, Patel KU, et al. DefiningCoronary Flow Patterns: Comprehensive Automation ofTransthoracic Doppler Coronary Blood Flow[ J] . Sci Rep,2018,8( 1) :17268.
[10]胡国恒,王瑾茜,刘侃,等.益气活血组方治疗冠心病心肌缺血的临床观察[J].中国中医急症,2016,25(10):1940-1942.
[11]唐胜,沈建锋,谢玉华,等.自拟益气活血方治疗冠心病慢性心力衰竭临床效果及对炎症因子水平的影响[J].河北中医药学报,2018,33(1):11-14.
[12] Mehta SR. Nonculprit Lesion Intervention: 1 Step Closerto the COMPLETE Answer[ J] . JACC Cardiovasc Interv,2018,11( 22) :2274 -2275.
[13]汪强,谷惠敏,朱建中,等.补阳还五汤治疗气虚血瘀型冠心病心绞痛的临床回顾性研究[J].南京中医药大学学报,2017,33(6):579-582.
[14] Hu PT, Jones WS, Glorioso TJ, et al. Predictors andOutcomes of Staged Versus One - Time Multivessel Revascularization in Multivessel Coronary Artery Disease: Insights From the VA CART Program[ J] . JACC Cardiovasc Interv, 2018,11( 22) :2265 -2273.
[15]郑丽莉.芎归六君子汤对实验性大鼠冠心病的治疗作用[J].中国比较医学杂志,2018,28(1):23-27,55.
[16] Garcia S, Bhatt DL, Gallagher M, et al. Strategies toReduce Acute Kidney Injury and Improve Clinical Outcomes Following Percutaneous Coronary Intervention: A Subgroup Analysis of the PRESERVE Trial [ J] . JACCCardiovasc Interv, 2018,11( 22) :2254 -2261.

相似文献/References:

[1]李彤 张翠英.中医治疗冠心病伴焦虑抑郁症的临床研究进展[J].现代中医药,2018,(05):124.[doi:10.13424/j.cnki.mtcm.2018.05.041]
 Li Tong Zhang Cuiying.Clinical Research Progress of Traditional Chinese Medicine in Treating Coronary Heart Disease with Anxiety and Depression[J].Modern Traditional Chinese Medicine,2018,(03):124.[doi:10.13424/j.cnki.mtcm.2018.05.041]
[2]师永社.温阳益气逐瘀汤对心肾阳虚型冠心病中医证候积分及血管内皮功能的疗效观察[J].现代中医药,2020,(01):072.[doi:10.13424/j.cnki.mtcm.2020.01.020]
[3]王燕 吴晖 吴诗青.耳穴贴压联合正念减压疗法对冠心病PCI术后心理障碍患者生活质量的影响[J].现代中医药,2021,(01):086.[doi:10.13424/j.cnki.mtcm.2021.01.021]
 WANG Yan,WU Hui,WU Shi - qing.Effects of Auricular Point Sticking Combined with Mindfulness Decompression Therapy on Life Quality of Patients with Psychological Disorders after Percutaneous Coronary Intervention[J].Modern Traditional Chinese Medicine,2021,(03):086.[doi:10.13424/j.cnki.mtcm.2021.01.021]
[4]田永仓 赵丹 柏本健 康小琴 聂太宝 韦庄怡 王敏.当归补血方对冠状动脉搭桥术后 心功能及血清IL-6、NT-proBNP的影响[J].现代中医药,2022,1(01):127.[doi:10.13424/j.cnki.mtcm.2022.01.026]
 TIAN Yongcang ZHAO Dan BAI Benjian KANG Xiaoqin NIE Taibao WEI Zhuangyi WANG Min.Effects of Danggui Buxue Recipe on Cardiac Function and Serum IL-6 and NT-proBNP After Coronary Artery Bypass Grafting[J].Modern Traditional Chinese Medicine,2022,1(03):127.[doi:10.13424/j.cnki.mtcm.2022.01.026]
[5]杨杰 彭启伦 郭步伐 丁维俊.半夏-附子药对拮抗冠心病分子机制研究[J].现代中医药,2022,1(02):054.[doi:10.13424/j.cnki.mtcm.2022.02.010]
[6]赵梦尧 王樱儒 郭景瑞 韩选明.小青龙汤联合六君子汤加味治疗小儿支气管哮喘临床研究[J].现代中医药,2022,1(04):131.[doi:10.13424/j.cnki.mtcm.2022.04.025]

更新日期/Last Update: 2019-05-15