[1]姜小艳 唐海鸿 魏春山 童光东 周大桥 黄彬.软肝汤联合熊去氧胆酸治疗原发性胆汁性胆管炎 ３１例[J].现代中医药,2018,(06):033-35.[doi:10.13424/j.cnki.mtcm.2018.06.013]
　Jiang Xiaoyan Tang Haihong Wei Chunshan Tong Guangdong Zhou Daqiao Huang Bin.Treatment of 31 Cases of Primary Biliary Cholangitis with Ruangan Decoction Combined with Ursodeoxycholic Acid[J].Modern Traditional Chinese Medicine,2018,(06):033-35.[doi:10.13424/j.cnki.mtcm.2018.06.013]
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软肝汤联合熊去氧胆酸治疗原发性胆汁性胆管炎 ３１例()
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2018年06期
页码:
033-35
栏目:
临床研究
出版日期:
2018-11-18

文章信息/Info

Title:
Treatment of 31 Cases of Primary Biliary Cholangitis with Ruangan Decoction Combined with Ursodeoxycholic Acid
文章编号:
1672－0571(2018)06－0033－04
作者:
姜小艳 1 唐海鸿 2 魏春山 2 童光东 2 周大桥 2 黄彬 2
1.广州中医药大学第四临床医学院，广东 深圳 ５１８０３３；2.深圳市中医院，广东 深圳 ５１８０３３
Author(s):
Jiang Xiaoyan 1 Tang Haihong 2 Wei Chunshan 2 Tong Guangdong 2 Zhou Daqiao 2 Huang Bin 2
1． The Forth Clinical Medicine School of Guangzhou University of Chinese Medicine，Shenzhen China，518033; 2． Shenzhen TCM Hospital，Shen Zhen China，518033
关键词:
原发性胆汁性胆管炎; 中药; 熊去氧胆酸; 软肝汤
Keywords:
knee osteoarthritis;  method of invigorating kidney and boosting Qi;  Chinese medicine treatment;  quali- ty of life
分类号:
R575. 7
DOI:
10.13424/j.cnki.mtcm.2018.06.013
文献标志码:
B
摘要:
目的 软肝汤联合熊去氧胆酸治疗原发性胆汁性胆管炎的临床疗效。方法 收集我院门诊 ２０１６．５～ ２０１７．５就诊的 ６４例 ＰＢＣ患者，按数字表法随机分为对照组和治疗组，接受 ６个月的药物治疗及治疗期间的随 访。对照组服用熊去氧胆酸胶囊，治疗组服用软肝汤联合熊去氧胆酸治疗。观察对比患者酶学指标、免疫指标、 Ｆｉｒｂｓｃａｎ值、证候积分及有效率。结果 治疗前治疗组 ＴＢ水平较对照组高（Ｐ＜０．０５），余项基线指标未见差异； 治疗后治疗组 ＡＬＴ、ＡＳＴ、ＧＧＴ、ＴＢ、ＡＬＰ、ＩｇＭ、ＩｇＧ、补体 Ｃ３、Ｆｉ
Abstract:
To observe the clinical effect of Ruangan decoction combined with ursodeoxy- cholic acid in treating primary biliary cholangitis． Method: Sixty － four patients with primary biliary cholangitis (PBC) from 2016． 5 to 2017． 5 in Shenzhen TCM Hospital were randomly divided into con- trol group and treatment group according to the number table method． They were treated with drugs for 6 months and followed up during the treatment period． The control group was treated with Ursodeoxycholic Acid Capules，and the treatment group was treated with Rugan decoction combined with ursodeoxycholic acid． The enzyme，immune index，Firbscan value，syndrome score and effective rate were observed and compared． Result: The TB level in the treatment group before treatment was higher than that in the con- trol group (P ＜ 0． 05)，and there was no difference in the remaining baseline indicators． After treat- ment，ALT，AST，GGT，TB，ALP，IgM，Ig g，complement C3，Firbscan values and syndrome scores showed significant differences in the treatment group，the differences were statistically significant(P ＜ 0． 05)． ALT，AST，GGT，TB，ALP，Ig g and Firbscan values showed significant differences in thecontrol group，the differences were statistically significant(P ＜0． 05)． The total effective rate of GGT、 TB、ALP、IgM、Ig g、Firbsca values and syndrome scores in the treatment group were better than those in the control group (P ＜ 0． 05)． No adverse events occurred during the treatment． Conclusion: Ruangan decoction combined with ursodeoxycholic acid is effective and safe in the treatment of primary biliary cholangitis．

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备注/Memo

备注/Memo:
收稿日期:2017 －11 －01 编辑:杨芳艳
更新日期/Last Update: 2019-12-09