[1]陶文婷 许培箴沈建峰 陆振娟 刘二平 张克良.小半夏汤协同防治妇科肿瘤化疗性 恶心呕吐临床研究[J].现代中医药,2021,(05):076-80.[doi:10.13424/j.cnki.mtcm.2021.05.014]
　TAO Wenting XU Peizhen SHEN Jianfeng LU ZhenjuanLIU Erping ZHANG Keliang.Clinical Study of Xiaobanxia Decoction in The Prevention and Treatment of Chemotherapy-induced Nausea and Vomiting in Gynecological Tumors[J].Modern Traditional Chinese Medicine,2021,(05):076-80.[doi:10.13424/j.cnki.mtcm.2021.05.014]
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小半夏汤协同防治妇科肿瘤化疗性 恶心呕吐临床研究
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2021年05期
页码:
076-80
栏目:
临床精粹
出版日期:
2021-09-23

文章信息/Info

Title:
Clinical Study of Xiaobanxia Decoction in The Prevention and Treatment of Chemotherapy-induced Nausea and Vomiting in Gynecological Tumors
文章编号:
1672-0571(2021)05-0076-05
作者:
陶文婷1 许培箴1沈建峰2 陆振娟1 刘二平1 张克良1
1.南京医科大学附属常州妇幼保健院药事科，江苏 常州 213003；
2.常州市钟楼区北港街道社区卫生服务中心药剂科，江苏 常州 213003
Author(s):
TAO Wenting1 XU Peizhen1 SHEN Jianfeng2 LU Zhenjuan1LIU Erping1 ZHANG Keliang1
1.Department of Pharmacy，Changzhou Maternal and Child Health Hospital Affiliated to Nanjing Medical University，Jiangsu Changzhou 213003，China;
2.Pharmacy Department of Community Health Service Center，Beigang street，Zhonglou District，Changzhou City，Jia
关键词:
小半夏汤; 妇科肿瘤; 化疗; 恶心; 呕吐
Keywords:
Xiaobanxia decoction; Gynecological tumors; Chemotherapy; Nausea; Vomiting
分类号:
R730.53
DOI:
10.13424/j.cnki.mtcm.2021.05.014
文献标志码:
A
摘要:
目的 观察小半夏汤协同防治妇科肿瘤化疗性恶心呕吐的临床疗效。方法 将100例妇科肿瘤化疗患者按照相同化疗方案随机分成两组，每组50例，对照组给予盐酸昂丹司琼注射液，治疗组联合使用小半夏汤，观察化疗后第1～7 d的食欲、恶心、呕吐等情况。结果 化疗后第1 d两组患者的食欲、恶心、呕吐等情况无明细差异（P＞0.05），而化疗后第2~6 d治疗组患者的食欲较好，恶心呕吐发生率低，差异有统计学意义（P＜005）。结论 小半夏汤可以明显改善妇科肿瘤化疗后延迟性恶心呕吐的发生及减轻恶心呕吐的程度。
Abstract:
Objective To explore the clinical effect of Xiaobanxia decoction on chemotherapy-induced nausea and vomiting in gynecological tumors.Methods 100 patients with gynecological tumors were randomly divided into two groups according to the same chemotherapy scheme，with 50 cases in each group.The control group was given ondansetron hydrochloride injection，and the treatment group was combined with Xiaobanxia decoction.The appetite，nausea and vomiting were observed from 1 to 7 days after chemotherapy.Results There was no significant difference in appetite，nausea and vomiting between the two groups on the first day after chemotherapy (P>0.05)，but the patients in the treatment group on the second to sixth days after chemotherapy had better appetite and lower incidence of nausea and vomiting (P<0.05).Conclusion Xiaobanxia decoction can significantly improve the occurrence of delayed nausea and vomiting after gynecological tumor chemotherapy and reduce the degree of nausea and vomiting.

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备注/Memo

备注/Memo:
基金项目：常州市科技局项目（2017327）；南京医科大学科技发展基金项目（2017NJMU046）
更新日期/Last Update: 2021-09-24