[1]周辉 闫俊 张洁.活血通痹膏联合TDP治疗对2型糖尿病下肢神经感觉及血流变化临床研究[J].现代中医药,2022,1(06):098-103.[doi:10.13424/j.cnki.mtcm.2022.06.020]
 ZHOU Hui YAN Jun ZHANG Jie.Effect of Huoxue Tongbi Plaster Combined with TDP on Neurosensation of Lower Limbsand Blood Flow Changes in Patients with Type 2 Diabetes Mellitus[J].Modern Traditional Chinese Medicine,2022,1(06):098-103.[doi:10.13424/j.cnki.mtcm.2022.06.020]
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活血通痹膏联合TDP治疗对2型糖尿病下肢神经感觉及血流变化临床研究
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
1
期数:
2022年06期
页码:
098-103
栏目:
临床精粹
出版日期:
2022-12-10

文章信息/Info

Title:
Effect of Huoxue Tongbi Plaster Combined with TDP on Neurosensation of Lower Limbsand Blood Flow Changes in Patients with Type 2 Diabetes Mellitus
文章编号:
1672-0571(2022)06-0098-06
作者:
周辉 闫俊 张洁
西安市第五医院神经内科,陕西 西安 710082
Author(s):
ZHOU Hui YAN Jun ZHANG Jie
Department of Neurology, Xi’an Fifth Hospital, Xi’an 710082,China
关键词:
关键词:2型糖尿病活血通痹膏神经感觉血流速度特定电磁波治疗仪
Keywords:
Key words:Type 2 diabetes mellitus Huoxue Tongbi plaster Neurosensory Blood flow velocity Specific electromagnetic wave therapeutic apparatus
分类号:
R255.4
DOI:
10.13424/j.cnki.mtcm.2022.06.020
文献标志码:
A
摘要:
摘 要:目的 研究活血通痹膏联合特定电磁波(thermal design power,TDP)治疗对2型糖尿病下肢神经感觉及血流变化的疗效。方法 收集310例确诊为2型糖尿病的患者下肢神经感觉及血流变化,按照随机数字表法分为4组。常规治疗组80例;常规治疗+活血通痹膏外敷组75例;常规治疗+TDP治疗组76例;常规治疗+活血通痹膏外敷+TDP治疗组79例,上述各组均治疗14 d为一个疗程,间断14 d后行下一疗程治疗,3个疗程后各组再次复查下肢周围神经及血管多普勒检查,分析各组治疗前后双下肢针刺觉、温凉觉、震动觉阈值,同时观察双下肢胫后动脉(PT)峰值流速、足背动脉(DP)峰值流速及踝肱指数(ABI)的变化情况。 结果 经治疗后常规治疗组、常规治疗+活血通痹膏外敷组、常规治疗+TDP治疗组针刺觉、触压觉、温凉觉、震动觉阈值指标较治疗前改善均不明显(P>0.05),常规治疗+活血通痹膏外敷+TDP治疗仪组治疗后针刺觉、温凉觉、震动觉阈值较治疗前明显改善(P<0.05);经治疗后常规治疗组PT及DP流速峰值、ABI较治疗前改善不明显(P>0.05),常规治疗+活血通痹膏外敷组、常规治疗+TDP治疗组、常规治疗+活血通痹膏外敷+TDP治疗仪组PT及DP流速峰值、ABI均较前显著改善(P<0.05),活血通痹膏外敷联合TDP治疗仪组改善最为明显(P<0.01)。结论 活血通痹膏外敷联合应用TDP治疗仪可明显改善2型糖尿病患者下肢神经感觉损害同时可增加下肢血流速度;上述两者方法单独应用对2型糖尿病患者下肢血流有一定的改善作用,而对神经损害的改善则功效不明。
Abstract:
Abstract:Objective To study the effect of Huoxue Tongbi plaster combined with specific electromagnetic wave (TDP) on the changes of nerve sensation and blood flow in lower limbs of type 2 diabetes mellitus.Methods 310 patients with type 2 diabetes mellitus were divided into 4 groups according to random number table. Routine treatment group 80 cases; 75 cases in routine treatment+external application of huoxue tongbi plaster group; 76 cases in the routine treatment+TDP treatment group; 79 cases in the routine treatment+external application of Huoxue Tongbi plaster+TDP treatment group. Each group was treated for 14 days as a course of treatment, and the next course of treatment was performed after 14 days of interruption. After 3 courses of treatment, each group rechecked the peripheral nerve and blood vessel Doppler examination of the lower extremities, analyzed the acupuncture sensation, temperature sensation and vibration sensation thresholds of both lower extremities before and after treatment. At the same time, the peak velocity of posterior tibial artery (PT), dorsal pedis artery (DP) and ankle brachial index (ABI) were observed. Results After treatment, the threshold values of acupuncture sensation, tactile sensation, cold sensation and vibration sensation in the routine treatment group, routine treatment+Huoxue Tongbi plaster external application group and routine treatment+TDP treatment group were not significantly improved compared with those before treatment (P>0.05). The threshold values of acupuncture sensation, cold sensation and vibration sensation in the routine treatment+Huoxue Tongbi plaster external application+TDP treatment instrument group were significantly improved compared with those before treatment (P<0.05); After treatment, PT and DP peak flow rate and ABI in the conventional treatment group were not significantly improved compared with those before treatment (P>0.05), while PT and DP peak flow rate and ABI in the conventional treatment+Huoxue Tongbi plaster external application group, conventional treatment+TDP treatment group, conventional treatment+Huoxue Tongbi plaster external application+TDP therapeutic instrument group were significantly improved compared with those before treatment (P<0.05), and the Huoxue Tongbi plaster external application combined with TDP therapeutic instrument group was the most significantly improved (P<0.01). Conclusion External application of Huoxue Tongbi plaster combined with TDP therapeutic instrument can significantly improve the lower limb neurosensory impairment and increase the lower limb blood flow velocity in patients with type 2 diabetes mellitus; The above two methods alone can improve the blood flow of lower limbs in patients with type 2 diabetes, while the improvement of nerve damage is unclear.

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备注/Memo

备注/Memo:
基金项目:西安市科技局社会发展引导计划(2017118SF/YX012);陕西省中医药管理局中医药科研项目(15-jc024);陕西省自然科学基金项目(2019SF-177);西安市第五医院院内课题(2021lc03)
更新日期/Last Update: 2022-11-28