[1]杨得振 惠阳 贾勇 田博 张锐 董明 冯飞雪 高磊 刘园蔚 程楠 侯俊明 ＊＊.莪黄灌肠液治疗直肠癌术后吻合口炎 ６７例[J].现代中医药,2018,(06):057-60.[doi:10.13424/j.cnki.mtcm.2018.06.020]
Yang Dezhen Hui Yang Jia Yong Tian Bo Zhang Rui
Dong Ming Feng Feixue Gao Lei Liu Yuanwei Cheng Nan Hou Junming.Treatment of 67 Cases of Anastomotic Stomatitis
after Rectal Cancer Operation with Curcumol Enema[J].Modern Traditional Chinese Medicine,2018,(06):057-60.[doi:10.13424/j.cnki.mtcm.2018.06.020]
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莪黄灌肠液治疗直肠癌术后吻合口炎 ６７例(
)
《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]
- 卷:
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- 期数:
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2018年06期
- 页码:
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057-60
- 栏目:
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临床研究
- 出版日期:
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2018-11-18
文章信息/Info
- Title:
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Treatment of 67 Cases of Anastomotic Stomatitis
after Rectal Cancer Operation with Curcumol Enema
- 文章编号:
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1672－0571(2018)06－0057－04
- 作者:
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杨得振 1 惠阳 2 贾勇 1 田博 1 张锐 1董明 1 冯飞雪 2 高磊 1 刘园蔚 1 程楠 1 侯俊明 1＊＊
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1.陕西中医药大学附属医院，陕西 咸阳 ７１２０００；２．陕西中医药大学，陕西 咸阳 ７１２０４６
- Author(s):
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Yang Dezhen Hui Yang Jia Yong Tian Bo Zhang Rui
Dong Ming Feng Feixue Gao Lei Liu Yuanwei Cheng Nan Hou Junming
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1． Affiliated Hospital of Shaanxi University of Chinese Medicine，Xianyang China，712000;
2． Shaanxi University of Chinese Medicine，Xianyang China，712046
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- 关键词:
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莪黄灌肠液; 直肠灌注; 直肠癌; 吻合口炎; 具核梭杆菌
- Keywords:
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curcumol enema; transrectal perfusion; rectal cancer; anastomotic stomatitis; FN
- 分类号:
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R735. 3
+ 7
- DOI:
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10.13424/j.cnki.mtcm.2018.06.020
- 文献标志码:
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B
- 摘要:
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目的 观察莪黄灌肠液（经直肠灌注）对直肠癌患者术后吻合口炎的疗效以及对吻合口处具核梭杆 菌生存情况的影响。方法 根据标准选择我院肿瘤外科自 ２０１５年 １０月 ～２０１７年 １０月行手术治疗的直肠癌患 者共计 ６７例，经乙状结肠镜检查，明确吻合口炎诊断的患者，予莪黄灌肠液直肠灌注，治疗 １４ｄ后通过复查乙状 结肠镜来观察吻合口炎变化情况及患者腹泻、便秘、肛门下坠、排便肛门疼痛感、大便隐血症状是否改善；治疗前 后，经肛镜下取吻合部样本、培养，对比吻合口处具核梭杆菌感染情况。结果 莪黄灌肠液经直肠灌注 １４ｄ
- Abstract:
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To observe the effect of curcumol enema (transrectal perfusion) on postopera-
tive anastomotic stomatitis in patients with rectal cancer and the effect on the survival of Fusarium oxys-
porum at the anastomosis． Method: 67 patients with rectal cancer who underwent surgical treatment in the
tumor surgery department from October 2015 to October 2017 were selected according to the standard．
After sigmoidoscopy，the patients diagnosed as anastomotic stomatitis were given rectal perfusion of cur-
cumol enema． After 14 days of treatment，the changes of anastomotic stomatitis，the improvement of di-
arrhea，constipation，anal fall，anal pain of bowel movement，and symptoms of fecal occult blood wereobserved by sigmoidoscopy． Before and after treatment，samples of anastomotic sites are taken and cul-
tured under anus microscope to compare the infection of fusobacterium nucleatum (FN) at anastomotic
sites． Result: After 14 days of rectal perfusion，9 cases (13． 4%) were cured，16 cases (23． 9%) re-
markably effective，36 cases (53． 7%) effective，6 cases (8． 9%) ineffective，the short － term effec-
tive rate was 91． 0%; the infection rate of FN before and after treatment were 67． 16% (45/67) and
28． 35% (19/67)，with P ＜0． 01 before and after treatment． Conclusion: Curcumol enema (transrectal
perfusion) on postoperative anastomotic stomatitis in patients with rectal cancer has satisfactory effect，
and can significantly improve postoperative discomfort and reduce the local infection rate of FN． It is
worthy of wide clinical application．
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备注/Memo
- 备注/Memo:
-
收稿日期:2018 －06 －05 编辑:杨芳艳＊
＊ ＊
基金项目:咸阳市科学研究项目(2014K04 －10);陕西省科技计划重点项目(2018 － ZDXM － SF －001)
通讯作者:侯俊明(1964 － )，男，主任医师，从事消化道与腺体肿瘤的基础与临床研究。E － mail:houjunming125@
163． Com
更新日期/Last Update:
2019-12-09