[1]郝轩 张军茹.基于肠道菌群对中医药防治H型高血压 的理论探讨[J].现代中医药,2022,1(05):081-88.[doi:10.13424/j.cnki.mtcm.2022.05.016]
　HAO Xuan ZHANG Junru.Theoretical Discussion on Prevention and Treatment of H-type Hypertension with Traditional Chinese Medicine Based on Intestinal Flora[J].Modern Traditional Chinese Medicine,2022,1(05):081-88.[doi:10.13424/j.cnki.mtcm.2022.05.016]
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基于肠道菌群对中医药防治H型高血压 的理论探讨
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
1
期数:
2022年05期
页码:
081-88
栏目:
临床精粹
出版日期:
2022-09-20

文章信息/Info

Title:
Theoretical Discussion on Prevention and Treatment of H-type Hypertension with Traditional Chinese Medicine Based on Intestinal Flora
文章编号:
1672-0571(2022)05-0081-08
作者:
郝轩1 张军茹2
1.陕西中医药大学，陕西 咸阳 712046；
2.陕西省中医医院，陕西 西安 710000
Author(s):
HAO Xuan1 ZHANG Junru2
1.Shaanxi University of Chinese Medicine，Shaanxi Xianyang 712046,China；
2.Shaanxi Provincial Hospital of Chinese Medicine，Xian 710000,China
关键词:
关键词：肠道菌群; H型高血压; 同型半胱氨酸; 中药; 复方制剂
Keywords:
Key words:Intestinal flora; H-type hypertension; Homocysteine; Chinese medicine; Compound preparation
分类号:
R259
DOI:
10.13424/j.cnki.mtcm.2022.05.016
文献标志码:
A
摘要:
摘 要： 肠道菌群（Gut Microbiota,GM）作为人体微生态系统的重要组成部分，在营养代谢和免疫调节方面都有着重要作用，直接或间接影响着人体的健康。多项临床研究应用基因测序技术发现GM多样性与菌群结构改变与高血压密切相关。高血压在我国发病率居高不下，其并发症致死率及致残率较高。在我国原性高血压中H型高血压占比达75%，所以治疗H型高血压是提高我国高血压控制率的关键。研究发现中医药在调节GM有着独特的优势，通过保护肠道益生菌、增加菌群丰富度、抑制有害菌生长，调节GM。通过综述近几年中医药在改善GM对H型高血压的影响，为中医药防治H型高血压提供理论思路。
Abstract:
Abstract：Gut microbiota (GM)，as an important part of human micro ecosystem，plays an important role in nutritional metabolism and immune regulation，directly or indirectly affecting human health.Through a number of clinical studies and the application of gene sequencing technology，it was found that the diversity and structural changes of intestinal flora were closely related to hypertension.Hypertension has a high incidence rate in incidence rate，with a high mortality and disability rate of complications.H-type hypertension accounts for 75% of primary hypertension in China，so the treatment of H-type hypertension is the key to improve the control rate of hypertension in China.The study found that traditional Chinese medicine has unique advantages in regulating intestinal flora by protecting intestinal probiotics，increasing the richness of flora，inhibiting the growth of harmful bacteria，and regulating intestinal flora.This paper reviews the effect of traditional Chinese medicine in improving intestinal flora on H-type hypertension in recent years，and provides theoretical ideas for the prevention and treatment of H-type hypertension with traditional Chinese medicine.

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备注/Memo

备注/Memo:
基金项目：国家中医药管理局-中医药传统知识收集整理项目（141020001）；陕西省中医药管理局资助项目（2021-ZZ-JC036）;陕西省科技厅项目2022JM-473）
更新日期/Last Update: 2022-09-21