[1]闫明霞.养心通痹汤联合常规溶栓治疗急性心肌梗死临床研究[J].现代中医药,2019,(03):038-41.[doi:10.13424/j.cnki.mtcm.2019.03.013]
　Yan Mingxia.Effect of Yangxin Tongbi Decoction Combined with Routine Thrombolytic Therapy on Patients with Acute Myocardial Infarction[J].Modern Traditional Chinese Medicine,2019,(03):038-41.[doi:10.13424/j.cnki.mtcm.2019.03.013]
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养心通痹汤联合常规溶栓治疗急性心肌梗死临床研究 ()
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《现代中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2019年03期
页码:
038-41
栏目:
临床研究
出版日期:
2019-05-30

文章信息/Info

Title:
Effect of Yangxin Tongbi Decoction Combined with Routine Thrombolytic Therapy on Patients with Acute Myocardial Infarction
文章编号:
1672-0571(2019)03-0038-04
作者:
闫明霞
山阳县中医院,陕西山阳726400
Author(s):
Yan Mingxia
Shanyang TCM Hospital, Shanyang Shaanxi, 726400
关键词:
急性心肌梗死; 心肌缺血; 再灌注损伤; 养心痛痹汤; 溶栓治疗
Keywords:
acute myocardial infarction;  myocardial ischemia;  reperfusion injury;  Yangxin Tongbi Decoction;  thrombolytic therapy
分类号:
R255.2
DOI:
10.13424/j.cnki.mtcm.2019.03.013
文献标志码:
A
摘要:
目的分析探讨养心通痹汤联合常规溶栓治疗对急性心肌梗死患者心肌缺血再灌注损伤指标的影响?方法按照随机数字表法将所有患者简单随机分为治疗组和对照组两组,所有患者均给予常规的溶栓治疗,治疗组患者则在此基础上联合使用中药养心痛痹汤进行治疗?记录两组患者治疗前后的肌酸激酶同工酶和肌酸激酶水平以及超敏C反应蛋白水平?高敏肌钙蛋白水平,比较两组患者治疗前后的左室射血分数和心肌梗死面积以及不良反应情况等?结果经过治疗后,两组患者的TNT-HS?CK-MB?CK?hs-CRP等水平均显著优于本组治疗前;治疗组患者治疗后的T
Abstract:
To explore the effect of Yangxin Tongbi Decoction combined with routine thrombolytic therapy on myocardial ischemia - reperfusion injury index in patients with acute myocardial infarction. Methods: According to the random number table method, all patients were randomly divided into treatment group and control group. All patients were given routine thrombolytic therapy, while patients in treatment group were treated with Yangxi Tongbi Decoction additionally. The levels of creatine kinase isoenzymes and creatine kinase, hypersensitive C - reactive protein and hypersensitive troponin were recorded before and after treatment. Left ventricular ejection fraction, myocardial infarction area and adverse reactions were compared between the two groups before and after treatment. Results: After treatment, the levels of TNT - HS, CK - MB, CK, hs - CRP in the two groups were significantly better than those before treatment; the levels of TNT - HS, CK - MB, CK, hs - CRP in the treatment group were significantly better than those in the control group. The left ventricular ejection fraction and myocardial infarction area of the two groups after 1 day and 7 days of treatment weresignificantly better than those before treatment; the left ventricular ejection fraction of the treatment group was significantly higher than that of the control group after 1 day of treatment and 7 days of treatment; the myocardial infarction area of the treatment group was significantly lower than that of the control group after 1 day of treatment and 7 days of treatment. The incidence of reperfusion arrhythmia and adverse cardiovascular events in the treatment group were 6. 67% and 6. 67%, respectively, lower than those in the control group ( 26. 27% and 33. 33%) . Conclusion: Conventional thrombolysis combined with Yangxin Tongbi Decoction can effectively improve the reperfusion injury in patients with acute myocardial infarction, and can effectively avoid adverse cardiovascular events and promote the recovery of left ventricular ejection function. It is worth popularizing in clinical practice.

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更新日期/Last Update: 2019-05-15